Taxilin Gamma (TXLNg)

[Edit]

LSR5; FIAT; CXorf15; ELRG; Environmental lipopolysaccharide-responding gene; Lipopolysaccharide-specific response protein 5; Factor inhibiting ATF4-mediated transcription

Taxilin Gamma (TXLNg)
TXLNg encodes a member of the taxilin family. The encoded protein binds to the C-terminal coiled-coil region of syntaxin family members 1A, 3A and 4A, and may play a role in intracellular vesicle trafficking. This gene is up-regulated by lipopolysaccharide and the gene product may be involved in cell cycle regulation. The related mouse protein was also shown to inhibit activating transcription factor 4-mediated transcription and thus regulate bone mass accrual. The deduced 528-amino acid protein has a calculated molecular mass of 60.6 kD. The long coiled-coil region of gamma-taxilin spans amino acids 134 to 450. Northern blot analysis detected a 4.6-kb transcript in all tissues examined, with highest expression in heart and skeletal muscle. A minor 2.4-kb transcript was detected in heart, placenta, and skeletal muscle.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Taxilin Gamma (TXLNg) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Taxilin Gamma (TXLNg) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Taxilin Gamma (TXLNg) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Taxilin Gamma (TXLNg) CLIA Kit Customized Service Offer
n/a ELISA Kit for Taxilin Gamma (TXLNg) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Taxilin Gamma (TXLNg) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Taxilin Gamma (TXLNg) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Taxilin Gamma (TXLNg) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Taxilin Gamma (TXLNg) CLIA Kit Customized Service Offer
n/a ELISA Kit for Taxilin Gamma (TXLNg) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Taxilin Gamma (TXLNg) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Taxilin Gamma (TXLNg) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Taxilin Gamma (TXLNg) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Taxilin Gamma (TXLNg) CLIA Kit Customized Service Offer
n/a ELISA Kit for Taxilin Gamma (TXLNg) ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence of the human X chromosome." Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Identification and characterization of taxilin isoforms."Biochem. Biophys. Res. Commun. 319:936-943(2004) [PubMed] [Europe PMC] [Abstract]
  5. "FIAT represses ATF4-mediated transcription to regulate bone mass in transgenic mice."J. Cell Biol. 169:591-601(2005) [PubMed] [Europe PMC] [Abstract]
  6. "A probability-based approach for high-throughput protein phosphorylation analysis and site localization."Nat. Biotechnol. 24:1285-1292(2006) [PubMed] [Europe PMC] [Abstract]
  7. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  8. "Over-expression and siRNA of a novel environmental lipopolysaccharide-responding gene on the cell cycle of the human hepatoma-derived cell line HepG2."Toxicology 243:303-310(2008) [PubMed] [Europe PMC] [Abstract]
  9. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  10. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  11. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  12. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  13. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  14. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]