≡

Tripartite Motif Containing Protein 47 (TRIM47)

[Edit]

GOA; RNF100; Gene overexpressed in astrocytoma protein; RING finger protein 100

Tripartite Motif Containing Protein 47 (TRIM47)
CCC N671
HGNC 19020
MGI 1917374
RGD 1597317
UniProt Q96LD4
The deduced 638-amino acid GOA protein contains an N-terminal ring finger domain, 2 B-box domains, and a coiled-coil domain, placing it in the RBCC (ring finger B-box coiled-coil) protein family. In addition, GOA contains a C-terminal B30.2 domain and 2 LXXLL motifs.
GOA shares highest sequence identity with the estrogen-responsive ring finger protein EFP (ZNF147). Northern blot analysis detected a 2.3-kb transcript that was significantly overexpressed in 6 of 7 high-grade astrocytomas and all 3 low-grade astrocytomas examined in comparison with normal brain. In normal tissues GOA was expressed at low levels comparable to those seen in normal brain, with the exception of kidney, in which expression was about 10-fold higher.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Tripartite Motif Containing Protein 47 (TRIM47) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Tripartite Motif Containing Protein 47 (TRIM47) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Tripartite Motif Containing Protein 47 (TRIM47) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Tripartite Motif Containing Protein 47 (TRIM47) CLIA Kit Customized Service Offer
n/a ELISA Kit for Tripartite Motif Containing Protein 47 (TRIM47) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Tripartite Motif Containing Protein 47 (TRIM47) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Tripartite Motif Containing Protein 47 (TRIM47) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Tripartite Motif Containing Protein 47 (TRIM47) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Tripartite Motif Containing Protein 47 (TRIM47) CLIA Kit Customized Service Offer
n/a ELISA Kit for Tripartite Motif Containing Protein 47 (TRIM47) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Tripartite Motif Containing Protein 47 (TRIM47) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Tripartite Motif Containing Protein 47 (TRIM47) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Tripartite Motif Containing Protein 47 (TRIM47) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Tripartite Motif Containing Protein 47 (TRIM47) CLIA Kit Customized Service Offer
n/a ELISA Kit for Tripartite Motif Containing Protein 47 (TRIM47) ELISA Kit Customized Service Offer
  1. "GOA, a novel gene encoding a ring finger B-box coiled-coil protein, is overexpressed in astrocytoma."Biochem. Biophys. Res. Commun. 286:574-579(2001) [PubMed] [Europe PMC] [Abstract]
  2. "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage." Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
  5. "A probability-based approach for high-throughput protein phosphorylation analysis and site localization."Nat. Biotechnol. 24:1285-1292(2006) [PubMed] [Europe PMC] [Abstract]
  6. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  7. "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]
  8. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]