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Calcium/Calmodulin Dependent Protein Kinase ID (CAMK1D)

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CKLiK; CaMKI-like protein kinase

Calcium/Calmodulin Dependent Protein Kinase ID (CAMK1D)
CCC N633
HGNC 19341
MGI 2442190
PubMed 18567820
UniProt Q8IU85
Wiki CAMK1D
CAMK1D is expressed in polymorphonuclear leukocytes (PMNs) and may be part of the chemokine signal transduction pathway that regulates granulocyte function.
The deduced 357-amino acid protein showed an apparent molecular mass of about 40 kD following in vitro translation. CKLIK shares 77% amino acid homology with calcium/calmodulin-dependent kinase-1 (CAMK1). RNase protection analysis detected high expression of CKLIK in PMNs, but showed no expression in monocytes, lymphocytes, or any of the lymphoid or myeloid cell lines examined.Similar results were found when the stem cells differentiated toward eosinophils in the presence of IL5. CKLIK activity was induced by IL8 in a myeloid cell line stably expressing CKLIK.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Calcium/Calmodulin Dependent Protein Kinase ID (CAMK1D) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Calcium/Calmodulin Dependent Protein Kinase ID (CAMK1D) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Calcium/Calmodulin Dependent Protein Kinase ID (CAMK1D) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Calcium/Calmodulin Dependent Protein Kinase ID (CAMK1D) CLIA Kit Customized Service Offer
n/a ELISA Kit for Calcium/Calmodulin Dependent Protein Kinase ID (CAMK1D) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Calcium/Calmodulin Dependent Protein Kinase ID (CAMK1D) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Calcium/Calmodulin Dependent Protein Kinase ID (CAMK1D) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Calcium/Calmodulin Dependent Protein Kinase ID (CAMK1D) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Calcium/Calmodulin Dependent Protein Kinase ID (CAMK1D) CLIA Kit Customized Service Offer
n/a ELISA Kit for Calcium/Calmodulin Dependent Protein Kinase ID (CAMK1D) ELISA Kit Customized Service Offer
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  2. "Identification and characterization of novel components of a Ca2+/calmodulin-dependent protein kinase cascade in HeLa cells."FEBS Lett. 550:57-63(2003) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence and comparative analysis of human chromosome 10." Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Characterization of the role of CaMKI-like kinase (CKLiK) in human granulocyte function."Blood 106:1076-1083(2005) [PubMed] [Europe PMC] [Abstract]
  6. "Prominent expression and activity-dependent nuclear translocation of Ca2+/calmodulin-dependent protein kinase Idelta in hippocampal neurons."Eur. J. Neurosci. 22:2697-2707(2005) [PubMed] [Europe PMC] [Abstract]
  7. "Spatiotemporal expression of four isoforms of Ca2+/calmodulin-dependent protein kinase I in brain and its possible roles in hippocampal dendritic growth."Neurosci. Res. 57:86-97(2007) [PubMed] [Europe PMC] [Abstract]
  8. "Calmodulin-kinases: modulators of neuronal development and plasticity."Neuron 59:914-931(2008) [PubMed] [Europe PMC] [Abstract]
  9. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  10. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  11. "Crystal structure of human calmodulin-dependent protein kinase 1D."Submitted (DEC-2006) to the PDB data bank
  12. "Patterns of somatic mutation in human cancer genomes." Nature 446:153-158(2007) [PubMed] [Europe PMC] [Abstract]