≡

Tetratricopeptide Repeat Domain Protein 7A (TTC7A)

[Edit]

TTC7

Tetratricopeptide Repeat Domain Protein 7A (TTC7A)
CCC N608
HGNC 19750
MGI 1920999
PubMed 23423984
RGD 1306211
UniProt Q9ULT0
Wiki TTC7A
The tetratricopeptide repeat (TPR) domain is defined by a degenerate consensus sequence of 34 amino acids. TPR domain-containing proteins, such as TTC7A, have diverse functions in cell cycle control, protein transport, phosphate turnover, and protein trafficking or secretion, and they can act as chaperones or scaffolding proteins .
The deduced protein contains more than 700 amino acids. RT-PCR ELISA detected low to intermediate expression in all adult and fetal tissues and specific brain regions examined.By analyzing genes located in a region of mouse chromosome 17 associated with abnormal iron homeostasis, White et al. (2005) cloned Ttc7a. The deduced protein contains 7 TPR repeats, each of which has a helix-snap domain and forms alpha-helix segments.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Tetratricopeptide Repeat Domain Protein 7A (TTC7A) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Tetratricopeptide Repeat Domain Protein 7A (TTC7A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Tetratricopeptide Repeat Domain Protein 7A (TTC7A) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Tetratricopeptide Repeat Domain Protein 7A (TTC7A) CLIA Kit Customized Service Offer
n/a ELISA Kit for Tetratricopeptide Repeat Domain Protein 7A (TTC7A) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Tetratricopeptide Repeat Domain Protein 7A (TTC7A) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Tetratricopeptide Repeat Domain Protein 7A (TTC7A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Tetratricopeptide Repeat Domain Protein 7A (TTC7A) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Tetratricopeptide Repeat Domain Protein 7A (TTC7A) CLIA Kit Customized Service Offer
n/a ELISA Kit for Tetratricopeptide Repeat Domain Protein 7A (TTC7A) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Tetratricopeptide Repeat Domain Protein 7A (TTC7A) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Tetratricopeptide Repeat Domain Protein 7A (TTC7A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Tetratricopeptide Repeat Domain Protein 7A (TTC7A) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Tetratricopeptide Repeat Domain Protein 7A (TTC7A) CLIA Kit Customized Service Offer
n/a ELISA Kit for Tetratricopeptide Repeat Domain Protein 7A (TTC7A) ELISA Kit Customized Service Offer
  1. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  2. "Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain."DNA Res. 6:329-336(1999) [PubMed] [Europe PMC] [Abstract]
  3. "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones."DNA Res. 9:99-106(2002) [PubMed] [Europe PMC] [Abstract]
  4. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
  7. "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."Mol. Cell 31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
  8. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  9. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  10. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  11. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  12. "Exome sequencing identifies mutations in the gene TTC7A in French-Canadian cases with hereditary multiple intestinal atresia."J. Med. Genet. 50:324-329(2013) [PubMed] [Europe PMC] [Abstract]