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Autophagy Related Protein 4B (ATG4B)

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Apg4B; AUTL1; Autophagin 1; Cysteine protease ATG4B; AUT-like 1 cysteine endopeptidase; Autophagy-related cysteine endopeptidase 1; Autophagy-related protein 4 homolog B

Autophagy Related Protein 4B (ATG4B)
CCC N522
HGNC 20790
MGI 1913865
PubMed 23093945
RGD 1309664
UniProt Q9Y4P1
Wiki ATG4B
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed.
ATG4B encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Autophagy Related Protein 4B (ATG4B) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Autophagy Related Protein 4B (ATG4B) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Autophagy Related Protein 4B (ATG4B) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Autophagy Related Protein 4B (ATG4B) CLIA Kit Customized Service Offer
n/a ELISA Kit for Autophagy Related Protein 4B (ATG4B) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Autophagy Related Protein 4B (ATG4B) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Autophagy Related Protein 4B (ATG4B) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Autophagy Related Protein 4B (ATG4B) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Autophagy Related Protein 4B (ATG4B) CLIA Kit Customized Service Offer
n/a ELISA Kit for Autophagy Related Protein 4B (ATG4B) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Autophagy Related Protein 4B (ATG4B) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Autophagy Related Protein 4B (ATG4B) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Autophagy Related Protein 4B (ATG4B) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Autophagy Related Protein 4B (ATG4B) CLIA Kit Customized Service Offer
n/a ELISA Kit for Autophagy Related Protein 4B (ATG4B) ELISA Kit Customized Service Offer
  1. "Human autophagins, a family of cysteine proteinases potentially implicated in cell degradation by autophagy."J. Biol. Chem. 278:3671-3678(2003) [PubMed] [Europe PMC] [Abstract]
  2. "LC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formation."J. Cell Sci. 117:2805-2812(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."DNA Res. 6:63-70(1999) [PubMed] [Europe PMC] [Abstract]
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  6. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
  7. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]