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Solute Carrier Family 35, Member D2 (SLC35D2)

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UGTrel8; SQV7L; HFRC; Homolog of Fringe connection protein 1; UDP-galactose transporter-related protein 8; UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporter

Solute Carrier Family 35, Member D2 (SLC35D2)
CCC N519
HGNC 20799
MGI 1917734
PubMed 15607426
RGD 1309518
UniProt Q76EJ3
SLC35D2 transported UDP-N-acetylglucosamine (UDP-GlcNAc), UDP-glucose, and GDP-mannose, with UDP-GlcNAc being the preferred substrate. SLC35D2 did not transport GDP-mannose following transfection in human colon carcinoma cells. Overexpression of SLC35D2 affected the heparan sulfate on the cell surface of the mammalian cells.
The deduced protein contains 10 transmembrane segments with cytosolic N and C termini. Northern blot analysis detected a 2.0-kb transcript. Highest expression was in liver, followed by heart, kidney, small intestine, placenta, lung, and peripheral blood leukocytes. Much lower expression was detected in skeletal muscle and spleen, and no expression was found in brain, colon, and thymus.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Solute Carrier Family 35, Member D2 (SLC35D2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Solute Carrier Family 35, Member D2 (SLC35D2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Solute Carrier Family 35, Member D2 (SLC35D2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Solute Carrier Family 35, Member D2 (SLC35D2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Solute Carrier Family 35, Member D2 (SLC35D2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Solute Carrier Family 35, Member D2 (SLC35D2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Solute Carrier Family 35, Member D2 (SLC35D2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Solute Carrier Family 35, Member D2 (SLC35D2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Solute Carrier Family 35, Member D2 (SLC35D2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Solute Carrier Family 35, Member D2 (SLC35D2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Solute Carrier Family 35, Member D2 (SLC35D2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Solute Carrier Family 35, Member D2 (SLC35D2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Solute Carrier Family 35, Member D2 (SLC35D2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Solute Carrier Family 35, Member D2 (SLC35D2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Solute Carrier Family 35, Member D2 (SLC35D2) ELISA Kit Customized Service Offer
  1. "Molecular cloning and characterization of a human multisubstrate specific nucleotide-sugar transporter homologous to Drosophila fringe connection."J. Biol. Chem. 279:26469-26474(2004) [PubMed] [Europe PMC] [Abstract]
  2. "Identification and characterization of human Golgi nucleotide sugar transporter SLC35D2, a novel member of the SLC35 nucleotide sugar transporter family."Genomics 85:106-116(2005) [PubMed] [Europe PMC] [Abstract]
  3. "DNA sequence and analysis of human chromosome 9." Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Three proteins involved in Caenorhabditis elegans vulval invagination are similar to components of a glycosylation pathway."Proc. Natl. Acad. Sci. U.S.A. 96:974-979(1999) [PubMed] [Europe PMC] [Abstract]
  6. "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]