Solute Carrier Family 39, Member 12 (SLC39A12)

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ZIP12; LZT-Hs8; Zrt-and Irt-like protein 12; LIV-1 subfamily of ZIP zinc transporter 8

Solute Carrier Family 39, Member 12 (SLC39A12)
Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A12 belongs to a subfamily of proteins that show structural characteristics of zinc transporters .
By searching databases for sequences similar to a unique motif within LIV1 (SLC39A6), Taylor and Nicholson (2003) identified SLC39A12, which they designated LZT-Hs8. The deduced 654-amino acid protein contains a long N terminus, followed by 8 putative transmembrane domains and a short C terminus. It also has a high histidine content, including a motif similar to the catalytic zinc-binding site of matrix metalloproteases.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Solute Carrier Family 39, Member 12 (SLC39A12) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Solute Carrier Family 39, Member 12 (SLC39A12) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Solute Carrier Family 39, Member 12 (SLC39A12) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Solute Carrier Family 39, Member 12 (SLC39A12) CLIA Kit Customized Service Offer
n/a ELISA Kit for Solute Carrier Family 39, Member 12 (SLC39A12) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Solute Carrier Family 39, Member 12 (SLC39A12) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Solute Carrier Family 39, Member 12 (SLC39A12) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Solute Carrier Family 39, Member 12 (SLC39A12) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Solute Carrier Family 39, Member 12 (SLC39A12) CLIA Kit Customized Service Offer
n/a ELISA Kit for Solute Carrier Family 39, Member 12 (SLC39A12) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Solute Carrier Family 39, Member 12 (SLC39A12) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Solute Carrier Family 39, Member 12 (SLC39A12) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Solute Carrier Family 39, Member 12 (SLC39A12) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Solute Carrier Family 39, Member 12 (SLC39A12) CLIA Kit Customized Service Offer
n/a ELISA Kit for Solute Carrier Family 39, Member 12 (SLC39A12) ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence and comparative analysis of human chromosome 10." Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Expressed sequence tag analysis of human RPE/choroid for the NEIBank project: over 6000 non-redundant transcripts, novel genes and splice variants."Mol. Vis. 8:205-220(2002) [PubMed] [Europe PMC] [Abstract]
  5. "Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions."Genome Res. 14:1711-1718(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Examination of the zinc transporter gene, SLC39A12."Schizophr. Res. 81:321-322(2006) [PubMed] [Europe PMC] [Abstract]
  7. "The consensus coding sequences of human breast and colorectal cancers." Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]