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THAP Domain Containing Protein 5 (THAP5)

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THAP Domain Containing Protein 5 (THAP5)
CCC N461
HGNC 23188
PubMed 21195082
UniProt Q7Z6K1
By searching databases, Roussigne et al. (2003) identified several proteins containing an N-terminal THAP domain, including THAP5. The THAP domain of the deduced 395-amino acid THAP5 protein includes a C2CH signature, an AVPTIF box, and several other conserved amino acids.
Hartz (2009) mapped the THAP5 gene to chromosome 7q31.1 based on an alignment of the THAP5 sequence with the genomic sequence.
The THAP domain includes a C2CH signature, an AVPTIF box, and several other conserved amino acids. It appears to be restricted to animal proteins and shows similarity to a DNA-binding domain of Drosophila P element transposase.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant THAP Domain Containing Protein 5 (THAP5) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to THAP Domain Containing Protein 5 (THAP5) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to THAP Domain Containing Protein 5 (THAP5) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for THAP Domain Containing Protein 5 (THAP5) CLIA Kit Customized Service Offer
n/a ELISA Kit for THAP Domain Containing Protein 5 (THAP5) ELISA Kit Customized Service Offer
  1. "Human chromosome 7: DNA sequence and biology." Science 300:767-772(2003) [PubMed] [Europe PMC] [Abstract]
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  3. "THAP5 is a human cardiac-specific inhibitor of cell cycle that is cleaved by the proapoptotic Omi/HtrA2 protease during cell death."Am. J. Physiol. 297:H643-H653(2009) [PubMed] [Europe PMC] [Abstract]