RNA Polymerase II, DNA Directed Polypeptide J2 (POLR2J2)

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RPB11b1

RNA Polymerase II, DNA Directed Polypeptide J2 (POLR2J2)
POLR2J2 is a member of the RNA polymerase II subunit 11 gene family, which includes three genes in a cluster on chromosome 7q22.1 and a pseudogene on chromosome 7p13. The founding member of this family, DNA directed RNA polymerase II polypeptide J, has been shown to encode a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This locus produces multiple, alternatively spliced transcripts that potentially express isoforms with distinct C-termini compared to DNA directed RNA polymerase II polypeptide J. Most or all variants are spliced to include additional non-coding exons at the 3' end which makes them candidates for nonsense-mediated decay (NMD). Consequently, it is not known if this locus expresses a protein or proteins in vivo.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant RNA Polymerase II, DNA Directed Polypeptide J2 (POLR2J2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to RNA Polymerase II, DNA Directed Polypeptide J2 (POLR2J2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to RNA Polymerase II, DNA Directed Polypeptide J2 (POLR2J2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for RNA Polymerase II, DNA Directed Polypeptide J2 (POLR2J2) CLIA Kit Customized Service Offer
n/a ELISA Kit for RNA Polymerase II, DNA Directed Polypeptide J2 (POLR2J2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant RNA Polymerase II, DNA Directed Polypeptide J2 (POLR2J2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to RNA Polymerase II, DNA Directed Polypeptide J2 (POLR2J2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to RNA Polymerase II, DNA Directed Polypeptide J2 (POLR2J2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for RNA Polymerase II, DNA Directed Polypeptide J2 (POLR2J2) CLIA Kit Customized Service Offer
n/a ELISA Kit for RNA Polymerase II, DNA Directed Polypeptide J2 (POLR2J2) ELISA Kit Customized Service Offer
  1. "A human RNA polymerase II subunit is encoded by a recently generated multigene family."BMC Mol. Biol. 2:14-14(2001) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence of human chromosome 7." Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The thymocyte-specific MAR binding protein, SATB1, interacts in vitro with a novel variant of DNA-directed RNA polymerase II, subunit 11."Genomics 79:809-817(2002) [PubMed] [Europe PMC] [Abstract]