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BMS1 Homolog (BMS1)

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BMS1L; BMS1-Like,Ribosome Assembly Protein; Ribosome biogenesis protein BMS1 homolog

BMS1 Homolog (BMS1)
CCC N420
HGNC 23505
MGI 2446132
PubMed 23785305
RGD 1308043
UniProt Q14692
Bms1 is required for viability in yeast. Using conditional mutant alleles of Bms1, they observed that depletion of Bms1 caused defects in cleavage and processing of yeast 35S pre-rRNA and the disappearance of 40S ribosomal subunits. Glycerol gradient analysis of Bms1 mutants and Rcl1 showed that Bms1 and Rcl1 cosediment together in the 10S complex and associate with nascent ribosomes. Immunoprecipitation studies showed that Bms1 associates with U3 snoRNA. Mutations of BMS1 amino acids implicated in GTP/GDP binding affected BMS1 activity in vivo.The deduced protein contains 1,285 amino acids. Northern blot analysis detected expression in all tissues examined.The deduced 1,183-amino acid yeast protein has a calculated molecular mass of 135.5 kD.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant BMS1 Homolog (BMS1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to BMS1 Homolog (BMS1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to BMS1 Homolog (BMS1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for BMS1 Homolog (BMS1) CLIA Kit Customized Service Offer
n/a ELISA Kit for BMS1 Homolog (BMS1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant BMS1 Homolog (BMS1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to BMS1 Homolog (BMS1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to BMS1 Homolog (BMS1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for BMS1 Homolog (BMS1) CLIA Kit Customized Service Offer
n/a ELISA Kit for BMS1 Homolog (BMS1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant BMS1 Homolog (BMS1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to BMS1 Homolog (BMS1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to BMS1 Homolog (BMS1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for BMS1 Homolog (BMS1) CLIA Kit Customized Service Offer
n/a ELISA Kit for BMS1 Homolog (BMS1) ELISA Kit Customized Service Offer
  1. "Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1."DNA Res. 3:17-24(1996) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence and comparative analysis of human chromosome 10." Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
  5. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  6. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  7. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  8. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  9. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  10. "BMS1 is mutated in aplasia cutis congenita."PLoS Genet. 9:E1003573-E1003573(2013) [PubMed] [Europe PMC] [Abstract]
  11. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]