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ATPase Type 13A3 (ATP13A3)

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AFURS1; ATPase Family Homolog Up Regulated In Senescence Cells; Probable cation-transporting ATPase 13A3

ATPase Type 13A3 (ATP13A3)
CCC N361
HGNC 24113
MGI 2685388
PubMed 11867234
RGD 1590881
UniProt Q9H7F0
Wiki ATP13A3
ATP13A3 is a member of the P-type ATPase family of proteins that transport a variety of cations across membranes. Other P-type ATPases include ATP7B and ATP7A.
The deduced 701-amino acid protein has a predicted molecular mass of 77.31 kD and contains an E1-E2 ATPase domain, a hydrolase domain, 3 predicted transmembrane domains, and a highly conserved ATPase phosphorylation site. ATP13A3 shares 46% identity with human ATP13A2. Northern blot analysis detected upregulated expression of AFURS1 in senescent kidney parenchymal cells compared to exponentially growing cells.ATP13A3 gene contains 18 exons. They suggested that the very long 5-prime UTR may form a secondary structure that mediates translational regulation.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPN361Hu01 Recombinant ATPase Type 13A3 (ATP13A3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to ATPase Type 13A3 (ATP13A3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to ATPase Type 13A3 (ATP13A3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for ATPase Type 13A3 (ATP13A3) CLIA Kit Customized Service Offer
n/a ELISA Kit for ATPase Type 13A3 (ATP13A3) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant ATPase Type 13A3 (ATP13A3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to ATPase Type 13A3 (ATP13A3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to ATPase Type 13A3 (ATP13A3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for ATPase Type 13A3 (ATP13A3) CLIA Kit Customized Service Offer
n/a ELISA Kit for ATPase Type 13A3 (ATP13A3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant ATPase Type 13A3 (ATP13A3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to ATPase Type 13A3 (ATP13A3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to ATPase Type 13A3 (ATP13A3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for ATPase Type 13A3 (ATP13A3) CLIA Kit Customized Service Offer
n/a ELISA Kit for ATPase Type 13A3 (ATP13A3) ELISA Kit Customized Service Offer
  1. "Cloning the AFURS1 gene which is up-regulated in senescent human parenchymal kidney cells."Gene 283:271-275(2002) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence, annotation and analysis of human chromosome 3." Nature 440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
  5. "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."Mol. Cell 31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
  6. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  7. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  8. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  9. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  10. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]