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Sorting And Assembly Machinery Component 50 Homolog (SAMM50)

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CGI-51; TRG-3; YNL026W; OMP85; TOB55; Transformation-related gene 3 protein

Sorting And Assembly Machinery Component 50 Homolog (SAMM50)
CCC N335
HGNC 24276
MGI 1915903
PubMed 23535911
RGD 1303219
UniProt Q9Y512
Wiki SAMM50
SAMM50 is a component of the sorting and assembly machinery (SAM) complex of the outer mitochondrial membrane. The SAM complex has a role in integrating beta-barrel proteins into the outer mitochondrial membrane.Humphries et al. (2005) found that continued expression of fluorescence-tagged human SAM50 in COS-7 cells impaired mitochondrial morphology and shortened cellular life span, indicating that the fusion protein was toxic. SAM50 was associated with a 200-kD protein complex that was distinct from the 380-kD translocase of the outer mitochondrial membrane (TOM) complex. RNA interference against SAM50 in human embryonic kidney cells reduced assembly of TOM40 (TOMM40), an essential component of the TOM complex involved in translocation and sorting of proteins into mitochondria.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Sorting And Assembly Machinery Component 50 Homolog (SAMM50) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Sorting And Assembly Machinery Component 50 Homolog (SAMM50) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Sorting And Assembly Machinery Component 50 Homolog (SAMM50) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Sorting And Assembly Machinery Component 50 Homolog (SAMM50) CLIA Kit Customized Service Offer
n/a ELISA Kit for Sorting And Assembly Machinery Component 50 Homolog (SAMM50) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Sorting And Assembly Machinery Component 50 Homolog (SAMM50) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Sorting And Assembly Machinery Component 50 Homolog (SAMM50) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Sorting And Assembly Machinery Component 50 Homolog (SAMM50) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Sorting And Assembly Machinery Component 50 Homolog (SAMM50) CLIA Kit Customized Service Offer
n/a ELISA Kit for Sorting And Assembly Machinery Component 50 Homolog (SAMM50) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Sorting And Assembly Machinery Component 50 Homolog (SAMM50) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Sorting And Assembly Machinery Component 50 Homolog (SAMM50) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Sorting And Assembly Machinery Component 50 Homolog (SAMM50) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Sorting And Assembly Machinery Component 50 Homolog (SAMM50) CLIA Kit Customized Service Offer
n/a ELISA Kit for Sorting And Assembly Machinery Component 50 Homolog (SAMM50) ELISA Kit Customized Service Offer
  1. "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics."Genome Res. 10:703-713(2000) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "A genome annotation-driven approach to cloning the human ORFeome."Genome Biol. 5:R84.1-R84.11(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The DNA sequence of human chromosome 22." Nature 402:489-495(1999) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Progress in the definition of a reference human mitochondrial proteome."Proteomics 3:157-167(2003) [PubMed] [Europe PMC] [Abstract]
  7. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  8. "ChChd3, an inner mitochondrial membrane protein, is essential for maintaining crista integrity and mitochondrial function."J. Biol. Chem. 286:2918-2932(2011) [PubMed] [Europe PMC] [Abstract]
  9. "MINOS1 is a conserved component of mitofilin complexes and required for mitochondrial function and cristae organization."Mol. Biol. Cell 23:247-257(2012) [PubMed] [Europe PMC] [Abstract]
  10. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]