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Family With Sequence Similarity 82, Member B (FAM82B)

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CGI-90; RMD-1; Regulator of microtubule dynamics protein 1

Family With Sequence Similarity 82, Member B (FAM82B)
CCC N333
HGNC 24285
MGI 1913552
PubMed 22912832
RGD 1563085
UniProt Q96DB5
RMD1, encoding a deduced 293-amino acid protein with multiple coiled-coil domains. By database searching, they identified 5 proteins related to RMD1 in C. elegans as well as putative homologs in human, mouse, Xenopus, and zebrafish, but not in Drosophila or yeast.
Three human homologs were identified: RMD1, RMD2 (FAM82A), and RMD3 (FAM82C). RMD1 encodes a deduced 314-amino acid protein with multiple coiled-coil domains. The human and C. elegans RMD1 proteins localize to spindle microtubules and spindle poles. C. elegans RMD1 binds to aurora B, a regulatory factor needed for correct attachments in the spindle, in vitro. Cosedimentation assays showed that human RMD proteins interact with microtubules

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Family With Sequence Similarity 82, Member B (FAM82B) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Family With Sequence Similarity 82, Member B (FAM82B) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Family With Sequence Similarity 82, Member B (FAM82B) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Family With Sequence Similarity 82, Member B (FAM82B) CLIA Kit Customized Service Offer
n/a ELISA Kit for Family With Sequence Similarity 82, Member B (FAM82B) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Family With Sequence Similarity 82, Member B (FAM82B) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Family With Sequence Similarity 82, Member B (FAM82B) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Family With Sequence Similarity 82, Member B (FAM82B) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Family With Sequence Similarity 82, Member B (FAM82B) CLIA Kit Customized Service Offer
n/a ELISA Kit for Family With Sequence Similarity 82, Member B (FAM82B) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Family With Sequence Similarity 82, Member B (FAM82B) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Family With Sequence Similarity 82, Member B (FAM82B) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Family With Sequence Similarity 82, Member B (FAM82B) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Family With Sequence Similarity 82, Member B (FAM82B) CLIA Kit Customized Service Offer
n/a ELISA Kit for Family With Sequence Similarity 82, Member B (FAM82B) ELISA Kit Customized Service Offer
  1. "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics."Genome Res. 10:703-713(2000) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "DNA sequence and analysis of human chromosome 8." Nature 439:331-335(2006) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "RMD-1, a novel microtubule-associated protein, functions in chromosome segregation in Caenorhabditis elegans."J. Cell Biol. 179:1149-1162(2007) [PubMed] [Europe PMC] [Abstract]
  6. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]