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Defective In Sister Chromatid Cohesion 1 (DSCC1)

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DCC1; Sister chromatid cohesion protein DCC1

Defective In Sister Chromatid Cohesion 1 (DSCC1)
CCC N301
HGNC 24453
MGI 1919357
PubMed 24465681
RGD 1561749
UniProt Q9BVC3
Wiki Dscc1
CHTF18, CHTF8, and DSCC1 are components of an alternative replication factor C (RFC) complex that loads PCNA onto DNA during S phase of the cell cycle.DSCC1 protein contains 393 amino acids and has a calculated molecular mass of 45 kD.
The deduced protein has a calculated molecular mass of 44.8 kD and has 2 regions that share a high degree of conservation with yeast Dscc1. Immunohistochemical analysis showed that CHTF18, CHTF8, and DSCC1 localized to nuclear heterochromatin in a diffuse manner and appeared less abundant in nucleoli. SDS/PAGE analysis detected DSCC1 with an apparent molecular mass of about 45 kD.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Defective In Sister Chromatid Cohesion 1 (DSCC1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Defective In Sister Chromatid Cohesion 1 (DSCC1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Defective In Sister Chromatid Cohesion 1 (DSCC1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Defective In Sister Chromatid Cohesion 1 (DSCC1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Defective In Sister Chromatid Cohesion 1 (DSCC1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Defective In Sister Chromatid Cohesion 1 (DSCC1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Defective In Sister Chromatid Cohesion 1 (DSCC1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Defective In Sister Chromatid Cohesion 1 (DSCC1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Defective In Sister Chromatid Cohesion 1 (DSCC1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Defective In Sister Chromatid Cohesion 1 (DSCC1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Defective In Sister Chromatid Cohesion 1 (DSCC1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Defective In Sister Chromatid Cohesion 1 (DSCC1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Defective In Sister Chromatid Cohesion 1 (DSCC1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Defective In Sister Chromatid Cohesion 1 (DSCC1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Defective In Sister Chromatid Cohesion 1 (DSCC1) ELISA Kit Customized Service Offer
  1. "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Cloning and characterization of hCTF18, hCTF8, and hDCC1. Human homologs of a Saccharomyces cerevisiae complex involved in sister chromatid cohesion establishment."J. Biol. Chem. 278:30051-30056(2003) [PubMed] [Europe PMC] [Abstract]
  5. "Cohesin acetylation speeds the replication fork."Nature 462:231-234(2009) [PubMed] [Europe PMC] [Abstract]
  6. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]