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TBC1 Domain Family, Member 3C (TBC1D3C)

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TBC1 Domain Family, Member 3C (TBC1D3C)
CCC N239
HGNC 24889
UniProt Q6IPX1
By genomic sequence analysis, Hodzic et al. (2006) identified 8 paralogs of the TBC1D3 gene on chromosome 17, including TBC1D3C, which they called paralog B. All TBC1D3 paralogs encode a deduced 549-amino acid protein, but missense changes at 6 residues among the paralogs result in 5 different TBC1D3 isoforms. The TBC1D3 paralogs appeared to be differentially expressed in human tissues.The TBC1D3 paralogs appeared to be differentially expressed in human tissues. TBC1D3 was the only paralog expressed in heart.
By genomic sequence analysis, Hodzic et al. (2006) identified 8 TBC1D3 paralogs, including the TBC1D3C gene, on chromosome 17q12. The paralogs are clustered in 2 groups of 4 genes, and each cluster spans approximately 400 kb.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant TBC1 Domain Family, Member 3C (TBC1D3C) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to TBC1 Domain Family, Member 3C (TBC1D3C) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to TBC1 Domain Family, Member 3C (TBC1D3C) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for TBC1 Domain Family, Member 3C (TBC1D3C) CLIA Kit Customized Service Offer
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  1. "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage." Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  3. "TBC1D3, a hominoid oncoprotein, is encoded by a cluster of paralogues located on chromosome 17q12."Genomics 88:731-736(2006) [PubMed] [Europe PMC] [Abstract]
  4. "Diversity of human copy number variation and multicopy genes."Science 330:641-646(2010) [PubMed] [Europe PMC] [Abstract]