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Sensor Of Single Stranded DNA Complex Subunit C (SOSSC)

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INIP; hSSBIP1; C9orf80; Single-stranded DNA-binding protein-interacting protein 1; INTS3 and NABP-interacting protein

Sensor Of Single Stranded DNA Complex Subunit C (SOSSC)
CCC N229
HGNC 24994
MGI 1913459
RGD 1307983
UniProt Q9NRY2
SOSSC is a subunit of single-stranded DNA (ssDNA)-binding complexes involved in the maintenance of genome stability. Coimmunoprecipitation analysis confirmed that SOSS complexes formed in HeLa cells independent of DNA damage. Recombinant heterotrimeric SOSS complexes specifically bound ssDNA, but not double-stranded DNA. S
OSSB and SOSSC bound overlapping regions on SOSSA, which served as the central assembly factor, and did not interact directly with each other. Both SOSS complexes and the CTIP (RBBP8)/RPA complex acted downstream of the MRE11-RAD50-NBS1 (NBN) complex and functioned in DNA damage repair.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Sensor Of Single Stranded DNA Complex Subunit C (SOSSC) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Sensor Of Single Stranded DNA Complex Subunit C (SOSSC) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Sensor Of Single Stranded DNA Complex Subunit C (SOSSC) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Sensor Of Single Stranded DNA Complex Subunit C (SOSSC) CLIA Kit Customized Service Offer
n/a ELISA Kit for Sensor Of Single Stranded DNA Complex Subunit C (SOSSC) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Sensor Of Single Stranded DNA Complex Subunit C (SOSSC) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Sensor Of Single Stranded DNA Complex Subunit C (SOSSC) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Sensor Of Single Stranded DNA Complex Subunit C (SOSSC) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Sensor Of Single Stranded DNA Complex Subunit C (SOSSC) CLIA Kit Customized Service Offer
n/a ELISA Kit for Sensor Of Single Stranded DNA Complex Subunit C (SOSSC) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Sensor Of Single Stranded DNA Complex Subunit C (SOSSC) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Sensor Of Single Stranded DNA Complex Subunit C (SOSSC) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Sensor Of Single Stranded DNA Complex Subunit C (SOSSC) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Sensor Of Single Stranded DNA Complex Subunit C (SOSSC) CLIA Kit Customized Service Offer
n/a ELISA Kit for Sensor Of Single Stranded DNA Complex Subunit C (SOSSC) ELISA Kit Customized Service Offer
  1. "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells." Genome Res. 10:1546-1560(2000) [PubMed] [Europe PMC] [Abstract]
  2. "DNA sequence and analysis of human chromosome 9." Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  5. "hSSB1 and hSSB2 form similar multiprotein complexes that participate in DNA damage response."J. Biol. Chem. 284:23525-23531(2009) [PubMed] [Europe PMC] [Abstract]
  6. "SOSS complexes participate in the maintenance of genomic stability."Mol. Cell 35:384-393(2009) [PubMed] [Europe PMC] [Abstract]