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YOD1 OTU Deubiquinating Enzyme 1 Homolog (YOD1)

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OTUD2; DUBA8; HIN7; Ubiquitin thioesterase OTU1; HIV-1-induced protease 7; OTU domain-containing protein 2

YOD1 OTU Deubiquinating Enzyme 1 Homolog (YOD1)
CCC N223
HGNC 25035
MGI 2442596
PubMed 19818707
RGD 1359726
UniProt Q5VVQ6
Deubiquitinating enzymes (DUBs) are proteases that specifically cleave ubiquitin linkages, negating the action of ubiquitin ligases. DUBA8 belongs to a DUB subfamily characterized by an ovarian tumor (OTU) domain.Kayagaki et al. (2007) identified ovarian tumor domain (OTU)-containing protein 2 (OTUD2) in a small interfering RNA (siRNA)-based screen for OTU deubiquitinating enzyme (DUB) family members. The 6,265-basepair mRNA contains an open reading frame (ORF) predicting a 348-amino acid protein. In addition to an OTU domain, the protein includes a zinc finger (ZNF) C2H2 domain.The YOD1 gene maps to chromosome 1q32.1.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant YOD1 OTU Deubiquinating Enzyme 1 Homolog (YOD1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to YOD1 OTU Deubiquinating Enzyme 1 Homolog (YOD1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to YOD1 OTU Deubiquinating Enzyme 1 Homolog (YOD1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for YOD1 OTU Deubiquinating Enzyme 1 Homolog (YOD1) CLIA Kit Customized Service Offer
n/a ELISA Kit for YOD1 OTU Deubiquinating Enzyme 1 Homolog (YOD1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant YOD1 OTU Deubiquinating Enzyme 1 Homolog (YOD1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to YOD1 OTU Deubiquinating Enzyme 1 Homolog (YOD1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to YOD1 OTU Deubiquinating Enzyme 1 Homolog (YOD1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for YOD1 OTU Deubiquinating Enzyme 1 Homolog (YOD1) CLIA Kit Customized Service Offer
n/a ELISA Kit for YOD1 OTU Deubiquinating Enzyme 1 Homolog (YOD1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant YOD1 OTU Deubiquinating Enzyme 1 Homolog (YOD1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to YOD1 OTU Deubiquinating Enzyme 1 Homolog (YOD1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to YOD1 OTU Deubiquinating Enzyme 1 Homolog (YOD1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for YOD1 OTU Deubiquinating Enzyme 1 Homolog (YOD1) CLIA Kit Customized Service Offer
n/a ELISA Kit for YOD1 OTU Deubiquinating Enzyme 1 Homolog (YOD1) ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence and biological annotation of human chromosome 1." Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  5. "Gene expression profiling in human fetal liver and identification of tissue- and developmental-stage-specific genes through compiled expression profiles and efficient cloning of full-length cDNAs."Genome Res. 11:1392-1403(2001) [PubMed] [Europe PMC] [Abstract]
  6. "The otubain YOD1 is a deubiquitinating enzyme that associates with p97 to facilitate protein dislocation from the ER."Mol. Cell 36:28-38(2009) [PubMed] [Europe PMC] [Abstract]
  7. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  8. "OTU deubiquitinases reveal mechanisms of linkage specificity and enable ubiquitin chain restriction analysis."Cell 154:169-184(2013) [PubMed] [Europe PMC] [Abstract]