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Transmembrane Protein 126A (TMEM126A)

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Transmembrane Protein 126A (TMEM126A)
CCC N186
HGNC 25382
MGI 1913521
PubMed 23500070
RGD 1305677
UniProt Q9H061
Wiki TMEM126A
TMEM126 protein contains a conserved domain defined by homology between TMEM126A lys5 to gly191 and TMEM126B asn45 to glu229. TMEM126A colocalized with mitochondrial complex II subunit 70 kD Fp (SDHA), complex IV subunit 1 (MTCO), ATP synthase subunit beta (ATP5B), and ATP synthase subunit alpha (ATP5A), supporting the mitochondrial localization of the protein. The fusion protein did not significantly colocalize with the markers of the Golgi apparatus, lysosomes, early endosomes, cytoskeleton, microtubule, or centrosome. RT-PCR on total RNA from various adult and fetal human tissues showed that TMEM126A is strongly expressed in the brain (whole), cerebellum, fetal brain, skeletal muscle, testis, fetal retinal pigmentary epithelium, and fetal retina.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Transmembrane Protein 126A (TMEM126A) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Transmembrane Protein 126A (TMEM126A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Transmembrane Protein 126A (TMEM126A) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Transmembrane Protein 126A (TMEM126A) CLIA Kit Customized Service Offer
n/a ELISA Kit for Transmembrane Protein 126A (TMEM126A) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Transmembrane Protein 126A (TMEM126A) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Transmembrane Protein 126A (TMEM126A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Transmembrane Protein 126A (TMEM126A) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Transmembrane Protein 126A (TMEM126A) CLIA Kit Customized Service Offer
n/a ELISA Kit for Transmembrane Protein 126A (TMEM126A) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Transmembrane Protein 126A (TMEM126A) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Transmembrane Protein 126A (TMEM126A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Transmembrane Protein 126A (TMEM126A) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Transmembrane Protein 126A (TMEM126A) CLIA Kit Customized Service Offer
n/a ELISA Kit for Transmembrane Protein 126A (TMEM126A) ELISA Kit Customized Service Offer
  1. "Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs." Genome Res. 11:422-435(2001) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Human chromosome 11 DNA sequence and analysis including novel gene identification." Nature 440:497-500(2006) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "TMEM126A, encoding a mitochondrial protein, is mutated in autosomal-recessive nonsyndromic optic atrophy."Am. J. Hum. Genet. 84:493-498(2009) [PubMed] [Europe PMC] [Abstract]
  6. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  7. "TMEM126A is a mitochondrial located mRNA (MLR) protein of the mitochondrial inner membrane."Biochim. Biophys. Acta 1830:3719-3733(2013) [PubMed] [Europe PMC] [Abstract]