Rho Guanine Nucleotide Exchange Factor 10 Like Protein (ARHGEF10L)

[Edit]

GrinchGEF; Rho guanine nucleotide exchange factor 10-like protein

Rho Guanine Nucleotide Exchange Factor 10 Like Protein (ARHGEF10L)
ARHGEF10L is a member of the RhoGEF family of guanine nucleotide exchange factors (GEFs) that activate Rho GTPases. The deduced 1,235-amino acid ARHGEF10L protein has a calculated molecular mass of 135 kD and shares 60% and 44% similarity with ARHGEF10 and ARHGEF17, respectively.
ARHGEF10L contains a DH domain, a WD40-like domain, and 2 membrane-spanning sequences. Northern blot analysis of human tissues detected expression of a 5-kb ARHGEF10L transcript in heart, liver, skeletal muscle, kidney, and pancreas. An additional 4-kb variant was detected in heart and skeletal muscle, and a 6-kb variant was detected in liver. ARHGEF10L functions as a RHO-specific guanine nucleotide exchange factor (GEF).

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Rho Guanine Nucleotide Exchange Factor 10 Like Protein (ARHGEF10L) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Rho Guanine Nucleotide Exchange Factor 10 Like Protein (ARHGEF10L) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Rho Guanine Nucleotide Exchange Factor 10 Like Protein (ARHGEF10L) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Rho Guanine Nucleotide Exchange Factor 10 Like Protein (ARHGEF10L) CLIA Kit Customized Service Offer
n/a ELISA Kit for Rho Guanine Nucleotide Exchange Factor 10 Like Protein (ARHGEF10L) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Rho Guanine Nucleotide Exchange Factor 10 Like Protein (ARHGEF10L) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Rho Guanine Nucleotide Exchange Factor 10 Like Protein (ARHGEF10L) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Rho Guanine Nucleotide Exchange Factor 10 Like Protein (ARHGEF10L) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Rho Guanine Nucleotide Exchange Factor 10 Like Protein (ARHGEF10L) CLIA Kit Customized Service Offer
n/a ELISA Kit for Rho Guanine Nucleotide Exchange Factor 10 Like Protein (ARHGEF10L) ELISA Kit Customized Service Offer
  1. "GrinchGEF -- a novel Rho-specific guanine nucleotide exchange factor."Biochem. Biophys. Res. Commun. 335:1280-1286(2005) [PubMed] [Europe PMC] [Abstract]
  2. "Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."DNA Res. 7:273-281(2000) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The DNA sequence and biological annotation of human chromosome 1." Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  7. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  8. "The consensus coding sequences of human breast and colorectal cancers." Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]