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SAP30 Like Protein (SAP30L)

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NS4ATP2; Histone deacetylase complex SAP30L; HCV non-structural protein 4A-transactivated protein 2; Sin3 corepressor complex SAP30L; Sin3-associated protein p30-like

SAP30 Like Protein (SAP30L)
CCC N150
HGNC 25663
MGI 1354709
PubMed 19015240
RGD 1309585
UniProt Q9HAJ7
The deduced 183-amino acid protein contains 2 potential N-glycosylation sites, 1 N-myristoylation site, and several phosphorylation sites. Transient transfection studies showed that SAP30L localized to the nucleus in small dense bodies that are not PML bodies. Mutation of the SAP30L nuclear localization signal caused the protein to also be expressed throughout the cytoplasm.
SAP30L shares 70% identity with SAP30 and 97% identity with mouse Sap30l. Northern blot detected a 1.30-kb transcript in all human tissues examined, with highest expression in testis, followed by heart, kidney, and placenta. A 6.5-kb transcript had high expression in brain and lung.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant SAP30 Like Protein (SAP30L) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to SAP30 Like Protein (SAP30L) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to SAP30 Like Protein (SAP30L) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for SAP30 Like Protein (SAP30L) CLIA Kit Customized Service Offer
n/a ELISA Kit for SAP30 Like Protein (SAP30L) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant SAP30 Like Protein (SAP30L) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to SAP30 Like Protein (SAP30L) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to SAP30 Like Protein (SAP30L) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for SAP30 Like Protein (SAP30L) CLIA Kit Customized Service Offer
n/a ELISA Kit for SAP30 Like Protein (SAP30L) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant SAP30 Like Protein (SAP30L) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to SAP30 Like Protein (SAP30L) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to SAP30 Like Protein (SAP30L) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for SAP30 Like Protein (SAP30L) CLIA Kit Customized Service Offer
n/a ELISA Kit for SAP30 Like Protein (SAP30L) ELISA Kit Customized Service Offer
  1. "TGF-beta induces the expression of SAP30L, a novel nuclear protein."BMC Genomics 4:53-53(2003) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence and comparative analysis of human chromosome 5." Nature 431:268-274(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "FEZ1 dimerization and interaction with transcription regulatory proteins involves its coiled-coil region."J. Biol. Chem. 281:9869-9881(2006) [PubMed] [Europe PMC] [Abstract]
  6. "SAP30L interacts with members of the Sin3A corepressor complex and targets Sin3A to the nucleolus."Nucleic Acids Res. 34:3288-3298(2006) [PubMed] [Europe PMC] [Abstract]
  7. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  8. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  9. "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]
  10. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]