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RNA Polymerase II Associated Protein 3 (RPAP3)

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RNA Polymerase II Associated Protein 3 (RPAP3)
CCC N107
HGNC 26151
MGI 1277218
PubMed 20864038
RGD 1303036
UniProt Q9H6T3
Jeronimo et al. (2007) identified RPAP3 as an RNA polymerase II-associated protein in HEK293 human embryonic kidney cells and obtained a full-length RPAP3 cDNA by database and sequence analyses. The deduced 665-amino acid protein contains 2 helix-turn-helix tetratricopeptide repeats characteristic of chaperone cofactors.
Examination of the protein interaction network revealed that the RPAPs and XAB1 also interacted with components of the Mediator and Integrator complexes, as well as with proteins able to assemble into molecular chaperone complexes, including the prefoldins and the AAA+ ATPases RUVBL1 and RUVBL2.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant RNA Polymerase II Associated Protein 3 (RPAP3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to RNA Polymerase II Associated Protein 3 (RPAP3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to RNA Polymerase II Associated Protein 3 (RPAP3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for RNA Polymerase II Associated Protein 3 (RPAP3) CLIA Kit Customized Service Offer
n/a ELISA Kit for RNA Polymerase II Associated Protein 3 (RPAP3) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant RNA Polymerase II Associated Protein 3 (RPAP3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to RNA Polymerase II Associated Protein 3 (RPAP3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to RNA Polymerase II Associated Protein 3 (RPAP3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for RNA Polymerase II Associated Protein 3 (RPAP3) CLIA Kit Customized Service Offer
n/a ELISA Kit for RNA Polymerase II Associated Protein 3 (RPAP3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant RNA Polymerase II Associated Protein 3 (RPAP3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to RNA Polymerase II Associated Protein 3 (RPAP3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to RNA Polymerase II Associated Protein 3 (RPAP3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for RNA Polymerase II Associated Protein 3 (RPAP3) CLIA Kit Customized Service Offer
n/a ELISA Kit for RNA Polymerase II Associated Protein 3 (RPAP3) ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The finished DNA sequence of human chromosome 12." Nature 440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme."Mol. Cell 27:262-274(2007) [PubMed] [Europe PMC] [Abstract]
  5. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  6. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  7. "PIH1D1, a subunit of R2TP complex, inhibits doxorubicin-induced apoptosis."Biochem. Biophys. Res. Commun. 403:340-344(2010) [PubMed] [Europe PMC] [Abstract]
  8. "CK2 phospho-dependent binding of R2TP complex to TEL2 is essential for mTOR and SMG1 stability."Mol. Cell 39:839-850(2010) [PubMed] [Europe PMC] [Abstract]
  9. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  10. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  11. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  12. "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]
  13. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]