N-Acetyltransferase 8 Like Protein (NAT8L)
[Edit]Hcml3; CML3; NAA synthetase; N-acetylaspartate synthetase; Camello-like protein 3
![N-Acetyltransferase 8 Like Protein (NAT8L)](/upload/item/img/N-Acetyltransferase-8-Like-Protein-(NAT8L)-82064.jpg)
By searching an EST database for sequences similar to Xenopus camello, Popsueva et al. (2001) identified NAT8L, which they called CML3. The deduced 144-amino acid protein has a hydrophobic domain in its N-terminal half and 3 motifs characteristic of an acetyltransferase in its C-terminal half. Hartz (2006) mapped the NAT8L gene to chromosome 4p16.3 based on an alignment of the NAT8L sequence with the genomic sequence (build 36.1).
N-acetyltransferase is an enzyme that catalyzes the transfer of acetyl groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPN064Hu01 | Recombinant N-Acetyltransferase 8 Like Protein (NAT8L) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAN064Hu21 | Monoclonal Antibody to N-Acetyltransferase 8 Like Protein (NAT8L) | WB; IHC; ICC; IP. |
PAN064Hu01 | Polyclonal Antibody to N-Acetyltransferase 8 Like Protein (NAT8L) | WB | |
Assay Kits | SEN064Hu | ELISA Kit for N-Acetyltransferase 8 Like Protein (NAT8L) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant N-Acetyltransferase 8 Like Protein (NAT8L) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to N-Acetyltransferase 8 Like Protein (NAT8L) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to N-Acetyltransferase 8 Like Protein (NAT8L) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for N-Acetyltransferase 8 Like Protein (NAT8L) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for N-Acetyltransferase 8 Like Protein (NAT8L) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant N-Acetyltransferase 8 Like Protein (NAT8L) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to N-Acetyltransferase 8 Like Protein (NAT8L) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to N-Acetyltransferase 8 Like Protein (NAT8L) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for N-Acetyltransferase 8 Like Protein (NAT8L) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for N-Acetyltransferase 8 Like Protein (NAT8L) | ELISA Kit Customized Service Offer |
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- "Overexpression of camello, a member of a novel protein family, reduces blastomere adhesion and inhibits gastrulation in Xenopus laevis."Dev. Biol. 234:483-496(2001) [PubMed] [Europe PMC] [Abstract]
- "Evidence for mitochondrial and cytoplasmic N-acetylaspartate synthesis in SH-SY5Y neuroblastoma cells."Neurochem. Int. 55:219-225(2009) [PubMed] [Europe PMC] [Abstract]
- "Molecular identification of aspartate N-acetyltransferase and its mutation in hypoacetylaspartia."Biochem. J. 425:127-136(2010) [PubMed] [Europe PMC] [Abstract]
- "Methamphetamine-induced neuronal protein NAT8L is the NAA biosynthetic enzyme: implications for specialized acetyl coenzyme A metabolism in the CNS."Brain Res. 1335:1-13(2010) [PubMed] [Europe PMC] [Abstract]