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Pleckstrin Homology Domain Containing Family A, Member 7 (PLEKHA7)

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Pleckstrin Homology Domain Containing Family A, Member 7 (PLEKHA7)
CCC N033
HGNC 27049
MGI 2445094
PubMed 22542108
RGD 1598216
UniProt Q6IQ23
Wiki PLEKHA7
The deduced 1,122-amino acid protein contains an N-terminal WW domain, followed by a pleckstrin (PLEK) homology region and a coiled-coil domain. Western blot analysis of Caco2 cells detected major and minor PLEKHA7 proteins with apparent molecular masses of 135 and 145 kD, respectively. Immunofluorescence analysis showed that PLEKHA7 localized to cell-cell junctions in Caco2 cells and colocalized with zona adherens proteins.
Protein pull-down assays revealed that PLEKHA7 interacted with the junctional protein Nezha. Depletion of PLEKHA7 reduced the amount of Nezha associated with cell junctions, and depletion of Nezha reciprocally altered the pattern of PLEKHA7 distribution.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Pleckstrin Homology Domain Containing Family A, Member 7 (PLEKHA7) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Pleckstrin Homology Domain Containing Family A, Member 7 (PLEKHA7) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Pleckstrin Homology Domain Containing Family A, Member 7 (PLEKHA7) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Pleckstrin Homology Domain Containing Family A, Member 7 (PLEKHA7) CLIA Kit Customized Service Offer
n/a ELISA Kit for Pleckstrin Homology Domain Containing Family A, Member 7 (PLEKHA7) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Pleckstrin Homology Domain Containing Family A, Member 7 (PLEKHA7) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Pleckstrin Homology Domain Containing Family A, Member 7 (PLEKHA7) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Pleckstrin Homology Domain Containing Family A, Member 7 (PLEKHA7) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Pleckstrin Homology Domain Containing Family A, Member 7 (PLEKHA7) CLIA Kit Customized Service Offer
n/a ELISA Kit for Pleckstrin Homology Domain Containing Family A, Member 7 (PLEKHA7) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Pleckstrin Homology Domain Containing Family A, Member 7 (PLEKHA7) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Pleckstrin Homology Domain Containing Family A, Member 7 (PLEKHA7) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Pleckstrin Homology Domain Containing Family A, Member 7 (PLEKHA7) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Pleckstrin Homology Domain Containing Family A, Member 7 (PLEKHA7) CLIA Kit Customized Service Offer
n/a ELISA Kit for Pleckstrin Homology Domain Containing Family A, Member 7 (PLEKHA7) ELISA Kit Customized Service Offer
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