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PHD Finger Protein 23 (PHF23)

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PDH-containing protein JUNE-1

PHD Finger Protein 23 (PHF23)
CCC M968
HGNC 28428
MGI 1925496
PubMed 19430464
UniProt Q9BUL5
By searching for genes in a region of chromosome 17 involved in a translocation associated with acute myeloid leukemia (AML), followed by 5-prime and 3-prime RACE, Reader et al. (2007) cloned 2 splice variants of PHF23 that differed in their 3-prime noncoding regions. The deduced 403-amino acid protein contains a C-terminal coiled-coiled domain and a plant homeodomain (PHD) finger. The PHD finger is a structural fold found in nuclear proteins that is coordinated by 2 zinc atoms and is predicted to mediate chromatin remodeling.
Using FISH and genomic sequence analysis, Reader et al. (2007) mapped the PHF23 gene to chromosome 17p13.The deduced chimeric protein contains the N-terminal half of NUP98 fused to the C-terminal functional domains of PHF23.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant PHD Finger Protein 23 (PHF23) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to PHD Finger Protein 23 (PHF23) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to PHD Finger Protein 23 (PHF23) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for PHD Finger Protein 23 (PHF23) CLIA Kit Customized Service Offer
n/a ELISA Kit for PHD Finger Protein 23 (PHF23) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant PHD Finger Protein 23 (PHF23) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to PHD Finger Protein 23 (PHF23) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to PHD Finger Protein 23 (PHF23) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for PHD Finger Protein 23 (PHF23) CLIA Kit Customized Service Offer
n/a ELISA Kit for PHD Finger Protein 23 (PHF23) ELISA Kit Customized Service Offer
  1. "A novel NUP98-PHF23 fusion resulting from a cryptic translocation t(11;17)(p15;p13) in acute myeloid leukemia."Leukemia 21:842-844(2007) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage." Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  6. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  7. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  8. "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]
  9. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]