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Chromatin Modifying Protein 7 (CHMP7)

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CHMP Family Member 7; Charged multivesicular body protein 7

Chromatin Modifying Protein 7 (CHMP7)
CCC M965
HGNC 28439
MGI 1913922
RGD 1308779
UniProt Q8WUX9
CHMP7 interacted with CHMP4B, but not with EAP20 (VPS25). Overexpression of fluorescence-tagged CHMP7 impaired transport of endocytosed EGF in the endosome-lysosome pathway. Moreover, overexpression of CHMP7 suppressed release of virus-like particles into the culture medium of cotransfected cells.
The deduced 453-amino acid protein contains an SNF7 (CHMP4A)-related domain with a coiled-coil region in its N-terminal half and an SNF7 domain with 2 coiled-coil regions in its C-terminal half. The N-terminal half of CHMP7 also has 2 putative calmodulin-binding IQ motifs and a clathrin-binding motif. Epitope-tagged CHMP7 showed diffuse cytoplasmic staining and a punctate pattern, especially in the perinuclear area.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Chromatin Modifying Protein 7 (CHMP7) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Chromatin Modifying Protein 7 (CHMP7) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Chromatin Modifying Protein 7 (CHMP7) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Chromatin Modifying Protein 7 (CHMP7) CLIA Kit Customized Service Offer
n/a ELISA Kit for Chromatin Modifying Protein 7 (CHMP7) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Chromatin Modifying Protein 7 (CHMP7) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Chromatin Modifying Protein 7 (CHMP7) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Chromatin Modifying Protein 7 (CHMP7) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Chromatin Modifying Protein 7 (CHMP7) CLIA Kit Customized Service Offer
n/a ELISA Kit for Chromatin Modifying Protein 7 (CHMP7) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Chromatin Modifying Protein 7 (CHMP7) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Chromatin Modifying Protein 7 (CHMP7) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Chromatin Modifying Protein 7 (CHMP7) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Chromatin Modifying Protein 7 (CHMP7) CLIA Kit Customized Service Offer
n/a ELISA Kit for Chromatin Modifying Protein 7 (CHMP7) ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  3. "DNA sequence and analysis of human chromosome 8." Nature 439:331-335(2006) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "CHMP7, a novel ESCRT-III-related protein, associates with CHMP4b and functions in the endosomal sorting pathway."Biochem. J. 400:23-32(2006) [PubMed] [Europe PMC] [Abstract]
  6. "A probability-based approach for high-throughput protein phosphorylation analysis and site localization."Nat. Biotechnol. 24:1285-1292(2006) [PubMed] [Europe PMC] [Abstract]
  7. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  8. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  9. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  10. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  11. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]