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Transmembrane Protein 113 (TMEM113)

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WDR82; WDR82A; SWD2; WD Repeat Domain 82

Transmembrane Protein 113 (TMEM113)
CCC M930
HGNC 28826
MGI 1924555
UniProt Q6UXN9
TMEM113 (WDR82) is a component of the mammalian SET1A/SET1B histone H3-Lys4 methyltransferase complexes . The International Radiation Hybrid Mapping Consortium mapped the TMEM113 gene to chromosome 3.
Scott (2007) mapped the TMEM113 gene to 3p21.1 based on an alignment of the TMEM113 sequence with genomic sequence (build 36.2).
A transmembrane protein is a protein that spans the entire biological membrane. Transmembrane proteins aggregate and precipitate in water. They require detergents or nonpolar solvents for extraction, although some of them (beta-barrels) can be also extracted using denaturing agents.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Transmembrane Protein 113 (TMEM113) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Transmembrane Protein 113 (TMEM113) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Transmembrane Protein 113 (TMEM113) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Transmembrane Protein 113 (TMEM113) CLIA Kit Customized Service Offer
n/a ELISA Kit for Transmembrane Protein 113 (TMEM113) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Transmembrane Protein 113 (TMEM113) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Transmembrane Protein 113 (TMEM113) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Transmembrane Protein 113 (TMEM113) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Transmembrane Protein 113 (TMEM113) CLIA Kit Customized Service Offer
n/a ELISA Kit for Transmembrane Protein 113 (TMEM113) ELISA Kit Customized Service Offer
  1. "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "CpG-binding protein (CXXC finger protein 1) is a component of the mammalian Set1 histone H3-Lys4 methyltransferase complex, the analogue of the yeast Set1/COMPASS complex."J. Biol. Chem. 280:41725-41731(2005) [PubMed] [Europe PMC] [Abstract]
  4. "CUL4-DDB1 ubiquitin ligase interacts with multiple WD40-repeat proteins and regulates histone methylation."Nat. Cell Biol. 8:1277-1283(2006) [PubMed] [Europe PMC] [Abstract]
  5. "Identification and characterization of the human Set1B histone H3-Lys4 methyltransferase complex."J. Biol. Chem. 282:13419-13428(2007) [PubMed] [Europe PMC] [Abstract]
  6. "Wdr82 is a C-terminal domain-binding protein that recruits the Setd1A Histone H3-Lys4 methyltransferase complex to transcription start sites of transcribed human genes."Mol. Cell. Biol. 28:609-618(2008) [PubMed] [Europe PMC] [Abstract]
  7. "Molecular regulation of H3K4 trimethylation by Wdr82, a component of human Set1/COMPASS."Mol. Cell. Biol. 28:7337-7344(2008) [PubMed] [Europe PMC] [Abstract]
  8. "Identification and characterization of a novel human PP1 phosphatase complex."J. Biol. Chem. 285:24466-24476(2010) [PubMed] [Europe PMC] [Abstract]
  9. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  10. "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]