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F-Box Protein 38 (FBXO38)

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MOKA; Fbx38; Modulator of KLF7 activity homolog; F-box only protein 38

F-Box Protein 38 (FBXO38)
CCC M928
HGNC 28844
MGI 2444639
PubMed 22699663
RGD 1311505
UniProt Q6PIJ6
The deduced 1,193-amino acid protein has a calculated molecular mass of about 140 kD. It contains an N-terminal F-box domain, followed by 3 nuclear export signals (NES) and 3 C-terminal nuclear localization signals. Moka also has a highly acidic stretch of about 100 amino acids, an asp-rich stretch, and a ser-rich stretch. In situ hybridization found Moka and Klf7 coexpressed in the developing mouse nervous system and in adult testis.
Overexpression in COS-7 cells indicated that Moka is posttranslationally modified, since the apparent molecular mass was greater than 140 kD. Fluorescence-tagged Moka localized to both the nuclear and cytosolic compartments of transfected COS-7 cells and mouse fibroblasts.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant F-Box Protein 38 (FBXO38) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to F-Box Protein 38 (FBXO38) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to F-Box Protein 38 (FBXO38) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for F-Box Protein 38 (FBXO38) CLIA Kit Customized Service Offer
n/a ELISA Kit for F-Box Protein 38 (FBXO38) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant F-Box Protein 38 (FBXO38) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to F-Box Protein 38 (FBXO38) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to F-Box Protein 38 (FBXO38) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for F-Box Protein 38 (FBXO38) CLIA Kit Customized Service Offer
n/a ELISA Kit for F-Box Protein 38 (FBXO38) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant F-Box Protein 38 (FBXO38) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to F-Box Protein 38 (FBXO38) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to F-Box Protein 38 (FBXO38) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for F-Box Protein 38 (FBXO38) CLIA Kit Customized Service Offer
n/a ELISA Kit for F-Box Protein 38 (FBXO38) ELISA Kit Customized Service Offer
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  7. "A dominant mutation in FBXO38 causes distal spinal muscular atrophy with calf predominance." Am. J. Hum. Genet. 93:976-983(2013) [PubMed] [Europe PMC] [Abstract]