![Malectin (MLEC)](/upload/item/img/Malectin-(MLEC)-81908.jpg)
Malectin: a novel carbohydrate-binding protein of the endoplasmic reticulum and a candidate player in the early steps of protein N-glycosylation.N-Glycosylation starts in the endoplasmic reticulum (ER) where a 14-sugar glycan composed of three glucoses, nine mannoses, and two N-acetylglucosamines (Glc(3)Man(9)GlcNAc(2)) is transferred to nascent proteins. The glucoses are sequentially trimmed by ER-resident glucosidases. The Glc(3)Man(9)GlcNAc(2) moiety is the substrate for oligosaccharyltransferase; the Glc(1)Man(9)GlcNAc(2) and Man(9)GlcNAc(2) intermediates are signals for glycoprotein folding and quality control in the calnexin/calreticulin cycle. Structure determination by nuclear magnetic resonance showed that its luminal part is a carbohydrate binding domain that recognizes glucose oligomers.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Malectin (MLEC) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Malectin (MLEC) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Malectin (MLEC) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Malectin (MLEC) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Malectin (MLEC) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Malectin (MLEC) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Malectin (MLEC) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Malectin (MLEC) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Malectin (MLEC) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Malectin (MLEC) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Malectin (MLEC) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Malectin (MLEC) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Malectin (MLEC) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Malectin (MLEC) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Malectin (MLEC) | ELISA Kit Customized Service Offer |
Organism species: Chicken (Gallus)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPM908Ga01 | Recombinant Malectin (MLEC) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAM908Ga01 | Polyclonal Antibody to Malectin (MLEC) | WB; IHC; ICC; IP. |
LAM908Ga71 | Biotin-Linked Polyclonal Antibody to Malectin (MLEC) | WB; IHC; ICC. | |
LAM908Ga81 | FITC-Linked Polyclonal Antibody to Malectin (MLEC) | WB; IHC; ICC; IF. | |
Assay Kits | n/a | CLIA Kit for Malectin (MLEC) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Malectin (MLEC) | ELISA Kit Customized Service Offer |
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- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]