Short Chain Dehydrogenase/Reductase Family 9C, Member 7 (SDR9C7)

[Edit]

SDR-O; RDHS; SDRO; Orphan short-chain dehydrogenase/reductase

Short Chain Dehydrogenase/Reductase Family 9C, Member 7 (SDR9C7)
Human SDRO encodes a 313-amino acid protein that shares 83% sequence identity with the mouse protein. Northern blot analysis on both mouse and human tissues revealed that SDRO is highly expressed in liver, with expression in mouse liver as early as embryonic day 7. A single 1.6-kb transcript is present in human tissues, whereas 4 transcripts are present in mouse tissues.
SDRO does not have retinoid, 3-alpha-, 17-beta- or 11-beta-hydroxysteroid dehydrogenase activities. They suggested that SDRO may catalyze the metabolism of another class of nuclear receptor ligands, or may regulate metabolism by binding substrates or products, or by serving as a regulatory factor.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Short Chain Dehydrogenase/Reductase Family 9C, Member 7 (SDR9C7) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Short Chain Dehydrogenase/Reductase Family 9C, Member 7 (SDR9C7) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Short Chain Dehydrogenase/Reductase Family 9C, Member 7 (SDR9C7) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Short Chain Dehydrogenase/Reductase Family 9C, Member 7 (SDR9C7) CLIA Kit Customized Service Offer
n/a ELISA Kit for Short Chain Dehydrogenase/Reductase Family 9C, Member 7 (SDR9C7) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Short Chain Dehydrogenase/Reductase Family 9C, Member 7 (SDR9C7) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Short Chain Dehydrogenase/Reductase Family 9C, Member 7 (SDR9C7) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Short Chain Dehydrogenase/Reductase Family 9C, Member 7 (SDR9C7) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Short Chain Dehydrogenase/Reductase Family 9C, Member 7 (SDR9C7) CLIA Kit Customized Service Offer
n/a ELISA Kit for Short Chain Dehydrogenase/Reductase Family 9C, Member 7 (SDR9C7) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Short Chain Dehydrogenase/Reductase Family 9C, Member 7 (SDR9C7) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Short Chain Dehydrogenase/Reductase Family 9C, Member 7 (SDR9C7) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Short Chain Dehydrogenase/Reductase Family 9C, Member 7 (SDR9C7) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Short Chain Dehydrogenase/Reductase Family 9C, Member 7 (SDR9C7) CLIA Kit Customized Service Offer
n/a ELISA Kit for Short Chain Dehydrogenase/Reductase Family 9C, Member 7 (SDR9C7) ELISA Kit Customized Service Offer
  1. "SDR-O: an orphan short-chain dehydrogenase/reductase localized at mouse chromosome 10/human chromosome 12."Gene 294:141-146(2002) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative."Chem. Biol. Interact. 178:94-98(2009) [PubMed] [Europe PMC] [Abstract]
  5. "In search for function of two human orphan SDR enzymes: Hydroxysteroid dehydrogenase like 2 (HSDL2) and short-chain dehydrogenase/reductase-orphan (SDR-O)."J. Steroid Biochem. Mol. Biol. 117:117-124(2009) [PubMed] [Europe PMC] [Abstract]
  6. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]