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Solute Carrier Family 25, Member 33 (SLC25A33)

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BMSC-MCP; PNC1; Bone marrow stromal cell mitochondrial carrier protein

Solute Carrier Family 25, Member 33 (SLC25A33)
CCC M877
HGNC 29681
MGI 1917806
UniProt Q9BSK2
SLC25A33 belongs to the SLC25 family of mitochondrial carrier proteins. BMSCMCP shares 28% identity with calcium-binding mitochondrial carrier protein Aralar (SLC25A12) and 28% identity with mitochondrial folate transporters . Northern blot analysis of human tissues detected abundant expression in testis and skeletal muscle, moderate expression in heart, brain, liver, kidney, prostate, colon, and peripheral blood leukocytes, but no expression in placenta, lung, pancreas, spleen, thymus, ovary, or small intestine.
PCR analysis detected BMSCMCP in most tumor cell lines examined as well as dendritic cells and BMSCs. Fluorescence-tagged BMSCMCP colocalized with a mitochondrial marker in a punctate cytoplasmic distribution and in pseudopodial protrusions.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Solute Carrier Family 25, Member 33 (SLC25A33) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Solute Carrier Family 25, Member 33 (SLC25A33) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Solute Carrier Family 25, Member 33 (SLC25A33) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Solute Carrier Family 25, Member 33 (SLC25A33) CLIA Kit Customized Service Offer
n/a ELISA Kit for Solute Carrier Family 25, Member 33 (SLC25A33) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Solute Carrier Family 25, Member 33 (SLC25A33) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Solute Carrier Family 25, Member 33 (SLC25A33) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Solute Carrier Family 25, Member 33 (SLC25A33) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Solute Carrier Family 25, Member 33 (SLC25A33) CLIA Kit Customized Service Offer
n/a ELISA Kit for Solute Carrier Family 25, Member 33 (SLC25A33) ELISA Kit Customized Service Offer
  1. "HuBMSC-MCP, a novel member of mitochondrial carrier superfamily, enhances dendritic cell endocytosis."Biochem. Biophys. Res. Commun. 314:292-300(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The insulin-like growth factor-I-mTOR signaling pathway induces the mitochondrial pyrimidine nucleotide carrier to promote cell growth."Mol. Biol. Cell 18:3545-3555(2007) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence and biological annotation of human chromosome 1." Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Fourteen novel human members of mitochondrial solute carrier family 25 (SLC25) widely expressed in the central nervous system."Genomics 88:779-790(2006) [PubMed] [Europe PMC] [Abstract]
  6. "Mitochondrial pyrimidine nucleotide carrier (PNC1) regulates mitochondrial biogenesis and the invasive phenotype of cancer cells."Oncogene 29:3964-3976(2010) [PubMed] [Europe PMC] [Abstract]
  7. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  8. "The human SLC25A33 and SLC25A36 genes of solute carrier family 25 encode two mitochondrial pyrimidine nucleotide transporters."J. Biol. Chem. 289:33137-33148(2014) [PubMed] [Europe PMC] [Abstract]