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F-Box Protein 42 (FBXO42)

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Fbx42; JFK; Just one F-box and Kelch domain-containing protein; F-box only protein 42

F-Box Protein 42 (FBXO42)
CCC M806
HGNC 29249
MGI 1924992
RGD 1304787
UniProt Q6P3S6
Members of the F-box protein family, such as FBXO42, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1, cullin, and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains.
The deduced protein contains at least 651 amino acids. RT-PCR ELISA detected intermediate expression in adult brain, testis, ovary, liver, and kidney, low expression in heart and fetal brain, and little to no expression in all other tissues examined. Low to intermediate expression was detected in all specific brain regions examined, with highest expression in amygdala and caudate nucleus.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPM806Hu01 Recombinant F-Box Protein 42 (FBXO42) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to F-Box Protein 42 (FBXO42) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to F-Box Protein 42 (FBXO42) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for F-Box Protein 42 (FBXO42) CLIA Kit Customized Service Offer
n/a ELISA Kit for F-Box Protein 42 (FBXO42) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant F-Box Protein 42 (FBXO42) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to F-Box Protein 42 (FBXO42) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to F-Box Protein 42 (FBXO42) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for F-Box Protein 42 (FBXO42) CLIA Kit Customized Service Offer
n/a ELISA Kit for F-Box Protein 42 (FBXO42) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant F-Box Protein 42 (FBXO42) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to F-Box Protein 42 (FBXO42) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to F-Box Protein 42 (FBXO42) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for F-Box Protein 42 (FBXO42) CLIA Kit Customized Service Offer
n/a ELISA Kit for F-Box Protein 42 (FBXO42) ELISA Kit Customized Service Offer
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  7. "JFK, a Kelch domain-containing F-box protein, links the SCF complex to p53 regulation."Proc. Natl. Acad. Sci. U.S.A. 106:10195-10200(2009) [PubMed] [Europe PMC] [Abstract]
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