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Functional Spliceosome Associated Protein 33 (fSAP33)

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ISY1; ISY1 Splicing Factor Homolog; Pre-mRNA-splicing factor ISY1 homolog

Functional Spliceosome Associated Protein 33 (fSAP33)
CCC M801
HGNC 29201
MGI 1923310
RGD 1307688
UniProt Q9ULR0
By sequencing clones obtained from a size-fractionated brain cDNA library, Hirosawa et al. (1999) cloned ISY1, which they designated KIAA1160. The deduced protein contains 351 amino acids. RT-PCR ELISA detected expression in all adult and fetal tissues examined, with highest levels in liver, lung, and ovary. Within specific adult brain regions, highest expression was in amygdala and cerebellum.
Using a yeast model, Villa and Guthrie (2005) presented evidence that ISY1 regulates the fidelity of pre-mRNA splicing.By radiation hybrid analysis, Hirosawa et al. (1999) mapped the ISY1 gene to chromosome 3.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Functional Spliceosome Associated Protein 33 (fSAP33) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Functional Spliceosome Associated Protein 33 (fSAP33) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Functional Spliceosome Associated Protein 33 (fSAP33) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Functional Spliceosome Associated Protein 33 (fSAP33) CLIA Kit Customized Service Offer
n/a ELISA Kit for Functional Spliceosome Associated Protein 33 (fSAP33) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Functional Spliceosome Associated Protein 33 (fSAP33) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Functional Spliceosome Associated Protein 33 (fSAP33) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Functional Spliceosome Associated Protein 33 (fSAP33) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Functional Spliceosome Associated Protein 33 (fSAP33) CLIA Kit Customized Service Offer
n/a ELISA Kit for Functional Spliceosome Associated Protein 33 (fSAP33) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Functional Spliceosome Associated Protein 33 (fSAP33) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Functional Spliceosome Associated Protein 33 (fSAP33) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Functional Spliceosome Associated Protein 33 (fSAP33) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Functional Spliceosome Associated Protein 33 (fSAP33) CLIA Kit Customized Service Offer
n/a ELISA Kit for Functional Spliceosome Associated Protein 33 (fSAP33) ELISA Kit Customized Service Offer
  1. "Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain."DNA Res. 6:329-336(1999) [PubMed] [Europe PMC] [Abstract]
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis."RNA 8:426-439(2002) [PubMed] [Europe PMC] [Abstract]
  4. "ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage."Science 316:1160-1166(2007) [PubMed] [Europe PMC] [Abstract]
  5. "Isolation of XAB2 complex involved in pre-mRNA splicing, transcription, and transcription-coupled repair."J. Biol. Chem. 283:940-950(2008) [PubMed] [Europe PMC] [Abstract]
  6. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
  7. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  8. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]