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HAUS Augmin Like Complex Subunit 5 (HAUS5)

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Dgt5

HAUS Augmin Like Complex Subunit 5 (HAUS5)
CCC M787
HGNC 29130
MGI 1919159
PubMed 22223457
UniProt O94927
HAUS5 is 1 of 8 subunits of the 390-kD human augmin complex, or HAUS complex. The augmin complex was first identified in Drosophila, and its name comes from the Latin verb 'augmentare,' meaning 'to increase.' The augmin complex is a microtubule-binding complex involved in microtubule generation within the mitotic spindle and is vital to mitotic spindle assembly .
The transcript contains several repetitive elements in its 3-prime end, and the deduced protein contains 641 amino acids. RT-PCR ELISA detected very high expression in brain, testis, and ovary. Moderate expression was detected in heart, lung, and kidney, and weak expression was detected in liver, skeletal muscle, pancreas, and spleen.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant HAUS Augmin Like Complex Subunit 5 (HAUS5) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to HAUS Augmin Like Complex Subunit 5 (HAUS5) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to HAUS Augmin Like Complex Subunit 5 (HAUS5) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for HAUS Augmin Like Complex Subunit 5 (HAUS5) CLIA Kit Customized Service Offer
n/a ELISA Kit for HAUS Augmin Like Complex Subunit 5 (HAUS5) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant HAUS Augmin Like Complex Subunit 5 (HAUS5) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to HAUS Augmin Like Complex Subunit 5 (HAUS5) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to HAUS Augmin Like Complex Subunit 5 (HAUS5) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for HAUS Augmin Like Complex Subunit 5 (HAUS5) CLIA Kit Customized Service Offer
n/a ELISA Kit for HAUS Augmin Like Complex Subunit 5 (HAUS5) ELISA Kit Customized Service Offer
  1. "Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."DNA Res. 5:355-364(1998) [PubMed] [Europe PMC] [Abstract]
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  3. "HAUS, the 8-subunit human augmin complex, regulates centrosome and spindle integrity."Curr. Biol. 19:816-826(2009) [PubMed] [Europe PMC] [Abstract]
  4. "The augmin complex plays a critical role in spindle microtubule generation for mitotic progression and cytokinesis in human cells."Proc. Natl. Acad. Sci. U.S.A. 106:6998-7003(2009) [PubMed] [Europe PMC] [Abstract]
  5. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  6. "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]