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PDS5, Regulator Of Cohesion Maintenance Homolog A (PDS5A)

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PIG54; SCC-112; Cell proliferation-inducing gene 54 protein; Sister chromatid cohesion protein 112

PDS5, Regulator Of Cohesion Maintenance Homolog A (PDS5A)
CCC M783
HGNC 29088
MGI 1918771
PubMed 22230297
RGD 1307094
UniProt Q29RF7
The deduced 1,297-amino acid protein had a calculated molecular mass of 146 kD. PDS5A contains an N-terminal RhoGEF domain, a leucine zipper domain, an N-adaptin domain, a SKP1 domain, 3 PEST sequences, 6 nuclear localization signals, and 2 sites for tyrosine phosphorylation. Northern blot analysis detected transcripts of about 7 and 8 kb with high expression in adult skeletal muscle, heart, placenta, liver, and kidney. Western blot analysis detected PDS5A at an apparent molecular mass of 150 kD in a human lung carcinoma cell line and in human colon, lung, ovary, breast, and kidney tissues. An additional band of about 65 kD was also detected in most of the 22 normal kidney tissues examined. Immunohistochemical analysis of breast cancer cells showed PDS5A localized to the nucleus.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant PDS5, Regulator Of Cohesion Maintenance Homolog A (PDS5A) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to PDS5, Regulator Of Cohesion Maintenance Homolog A (PDS5A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to PDS5, Regulator Of Cohesion Maintenance Homolog A (PDS5A) Polyclonal Antibody Customized Service Offer
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n/a ELISA Kit for PDS5, Regulator Of Cohesion Maintenance Homolog A (PDS5A) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant PDS5, Regulator Of Cohesion Maintenance Homolog A (PDS5A) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to PDS5, Regulator Of Cohesion Maintenance Homolog A (PDS5A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to PDS5, Regulator Of Cohesion Maintenance Homolog A (PDS5A) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for PDS5, Regulator Of Cohesion Maintenance Homolog A (PDS5A) CLIA Kit Customized Service Offer
n/a ELISA Kit for PDS5, Regulator Of Cohesion Maintenance Homolog A (PDS5A) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant PDS5, Regulator Of Cohesion Maintenance Homolog A (PDS5A) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to PDS5, Regulator Of Cohesion Maintenance Homolog A (PDS5A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to PDS5, Regulator Of Cohesion Maintenance Homolog A (PDS5A) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for PDS5, Regulator Of Cohesion Maintenance Homolog A (PDS5A) CLIA Kit Customized Service Offer
n/a ELISA Kit for PDS5, Regulator Of Cohesion Maintenance Homolog A (PDS5A) ELISA Kit Customized Service Offer
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