C-Type Lectin Domain Family 16, Member A (CLEC16A)

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Gop-1

C-Type Lectin Domain Family 16, Member A (CLEC16A)
By sequencing clones obtained from a size-fractionated brain cDNA library, Nagase et al. (1997) obtained a partial cDNA encoding CLEC16A, which they designated KIAA0350. RT-PCR detected CLEC16A expression in all tissues examined, with highest levels in kidney, testis, and ovary. Nakajima et al. extended the partial KIAA0350 sequence and found that the deduced full-length protein contains 1,062 amino acids.
In addition to confirming previously identified loci, they found that type 1 diabetes was significantly associated with variation within a 233-kb linkage disequilibrium block on chromosome 16p13 that contains the KIAA0350 gene, which is predicted to encode a sugar-binding, C-type lectin.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant C-Type Lectin Domain Family 16, Member A (CLEC16A) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to C-Type Lectin Domain Family 16, Member A (CLEC16A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to C-Type Lectin Domain Family 16, Member A (CLEC16A) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for C-Type Lectin Domain Family 16, Member A (CLEC16A) CLIA Kit Customized Service Offer
n/a ELISA Kit for C-Type Lectin Domain Family 16, Member A (CLEC16A) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant C-Type Lectin Domain Family 16, Member A (CLEC16A) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to C-Type Lectin Domain Family 16, Member A (CLEC16A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to C-Type Lectin Domain Family 16, Member A (CLEC16A) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for C-Type Lectin Domain Family 16, Member A (CLEC16A) CLIA Kit Customized Service Offer
n/a ELISA Kit for C-Type Lectin Domain Family 16, Member A (CLEC16A) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant C-Type Lectin Domain Family 16, Member A (CLEC16A) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to C-Type Lectin Domain Family 16, Member A (CLEC16A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to C-Type Lectin Domain Family 16, Member A (CLEC16A) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for C-Type Lectin Domain Family 16, Member A (CLEC16A) CLIA Kit Customized Service Offer
n/a ELISA Kit for C-Type Lectin Domain Family 16, Member A (CLEC16A) ELISA Kit Customized Service Offer
  1. "Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro."DNA Res. 4:141-150(1997) [PubMed] [Europe PMC] [Abstract]
  2. "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones."DNA Res. 9:99-106(2002) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene." Nature 448:591-594(2007) [PubMed] [Europe PMC] [Abstract]
  6. "The diabetes susceptibility gene Clec16a regulates mitophagy."Cell 157:1577-1590(2014) [PubMed] [Europe PMC] [Abstract]