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G Antigen 10 (GAGE10)

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G Antigen 10 (GAGE10)
CCC M769
HGNC 30968
UniProt A6NGK3
GAGE cancer/testis antigens are frequently expressed in many different types of cancer, whereas their expression in normal tissues is limited to the germ cells of the immune-privileged organs, testis and ovary . Human melanoma cells express several distinct antigens that are recognized by autologous cytolytic T lymphocytes. Gjerstorff and Ditzel (2008) provided a review of the structure and phylogeny of the GAGE family members and presented a revised nomenclature.
Gjerstorff and Ditzel (2008) reported that the GAGE10 gene has an 8.9-kb insertion relative to other genes in the GAGE gene cluster. The GAGE10 gene contains 5 exons spanning about 12.7 kb and has a LINE insertion.By genomic sequence analysis, Gjerstorff and Ditzel (2008) mapped the GAGE10 gene to the 5-prime end of a GAGE gene cluster on chromosome Xp11.23.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant G Antigen 10 (GAGE10) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to G Antigen 10 (GAGE10) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to G Antigen 10 (GAGE10) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for G Antigen 10 (GAGE10) CLIA Kit Customized Service Offer
n/a ELISA Kit for G Antigen 10 (GAGE10) ELISA Kit Customized Service Offer
  1. "The DNA sequence of the human X chromosome." Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
  2. "An overview of the GAGE cancer/testis antigen family with the inclusion of newly identified members."Tissue Antigens 71:187-192(2008) [PubMed] [Europe PMC] [Abstract]