The 1p breakpoint was situated approximately 13 Mb distal to the previously reported linkage locus at 1p34.1-p32 identified by linkage as the site of a gene responsible for congenital bilateral isolated ptosis (PTOS1), and did not disrupt the coding sequence, whereas the chromosome 8 breakpoint disrupted a gene homologous to the mouse zfh4 gene.
McMullan et al. (2002) identified 10 exons of the human ZFH4 gene covering approximately 161 kb of DNA; the translocation breakpoint occurred in intron 4. Murine zfh4 codes for a zinc finger homeodomain protein that is a transcription factor expressed in both muscle and nerve tissue. McMullan et al. (2002) proposed that human ZFH4 is a candidate gene for congenital bilateral isolated ptosis.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPM767Hu01 | Recombinant Zinc Finger Homeobox Protein 4 (ZFHX4) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAM767Hu01 | Polyclonal Antibody to Zinc Finger Homeobox Protein 4 (ZFHX4) | WB; IHC; ICC; IP. |
MAM767Hu21 | Monoclonal Antibody to Zinc Finger Homeobox Protein 4 (ZFHX4) | WB; IHC; ICC; IP. | |
Assay Kits | SEM767Hu | ELISA Kit for Zinc Finger Homeobox Protein 4 (ZFHX4) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Zinc Finger Homeobox Protein 4 (ZFHX4) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Zinc Finger Homeobox Protein 4 (ZFHX4) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Zinc Finger Homeobox Protein 4 (ZFHX4) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Zinc Finger Homeobox Protein 4 (ZFHX4) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Zinc Finger Homeobox Protein 4 (ZFHX4) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Zinc Finger Homeobox Protein 4 (ZFHX4) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Zinc Finger Homeobox Protein 4 (ZFHX4) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Zinc Finger Homeobox Protein 4 (ZFHX4) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Zinc Finger Homeobox Protein 4 (ZFHX4) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Zinc Finger Homeobox Protein 4 (ZFHX4) | ELISA Kit Customized Service Offer |
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