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Syntaxin Binding Protein 5 Like Protein (STXBP5L)

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LLGL4; Tomosyn-2; Lethal(2) giant larvae protein homolog 4

Syntaxin Binding Protein 5 Like Protein (STXBP5L)
CCC M739
HGNC 30757
MGI 2443815
PubMed 23223146
UniProt Q9Y2K9
The Drosophila gene Lethal giant larvae (Lgl) regulates epithelial polarity, and when mutated leads to tumor formation. Using homology searches with the human Lgl homolog LLGL1 as query, Katoh and Katoh (2004) identified the cDNA KIAA1006, which contained a homologous open reading frame that the authors named LLGL4.
The LLGL4 gene encodes a protein of 1,186 amino acids that shares 95.8% and 68.4% amino acid identity with mouse Llgl4 and human LLGL3, respectively. LLGL4 mRNA is expressed in hippocampus, kidney, lung carcinoid, and germ cell tumors. Sequence comparisons of LGL family members identified 3 conserved domains. In addition to these domains, LLGL4 contains 5 WD40 repeats and a C-terminal syntaxin-binding (STXB) domain.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Syntaxin Binding Protein 5 Like Protein (STXBP5L) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Syntaxin Binding Protein 5 Like Protein (STXBP5L) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Syntaxin Binding Protein 5 Like Protein (STXBP5L) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Syntaxin Binding Protein 5 Like Protein (STXBP5L) CLIA Kit Customized Service Offer
n/a ELISA Kit for Syntaxin Binding Protein 5 Like Protein (STXBP5L) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Syntaxin Binding Protein 5 Like Protein (STXBP5L) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Syntaxin Binding Protein 5 Like Protein (STXBP5L) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Syntaxin Binding Protein 5 Like Protein (STXBP5L) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Syntaxin Binding Protein 5 Like Protein (STXBP5L) CLIA Kit Customized Service Offer
n/a ELISA Kit for Syntaxin Binding Protein 5 Like Protein (STXBP5L) ELISA Kit Customized Service Offer
  1. "Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."DNA Res. 6:63-70(1999) [PubMed] [Europe PMC] [Abstract]
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Identification and characterization of human LLGL4 gene and mouse Llgl4 gene in silico."Int. J. Oncol. 24:737-742(2004) [PubMed] [Europe PMC] [Abstract]
  4. "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]