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Intraflagellar Transport Protein 172 (IFT172)

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SLB; Wim; Osm-1; Wimple Homolog

Intraflagellar Transport Protein 172 (IFT172)
CCC M700
HGNC 30391
MGI 2682064
PubMed 24140113
RGD 620744
UniProt Q9UG01
Rat Slb specifically binds to Lhx3 and Lhx4 with high affinity both in vitro and in vivo. Expression of the LIM-interacting domain of Slb reduced the expression of an Lhx3-responsive reporter gene.The 1,749-amino acid protein contains 7 N-terminal WD40 repeats and a nuclear localization signal. Highest expression was found in rat testis and pituitary cells.
The deduced protein contains 1,090 amino acids and shares significant homology with the kinesin light chain repeat sequence. RT-PCR analysis revealed highest expression of SLB in testis and lowest expression in spleen. All other tissues and brain regions tested showed low-to-moderate expression.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Intraflagellar Transport Protein 172 (IFT172) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Intraflagellar Transport Protein 172 (IFT172) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Intraflagellar Transport Protein 172 (IFT172) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Intraflagellar Transport Protein 172 (IFT172) CLIA Kit Customized Service Offer
n/a ELISA Kit for Intraflagellar Transport Protein 172 (IFT172) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Intraflagellar Transport Protein 172 (IFT172) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Intraflagellar Transport Protein 172 (IFT172) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Intraflagellar Transport Protein 172 (IFT172) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Intraflagellar Transport Protein 172 (IFT172) CLIA Kit Customized Service Offer
n/a ELISA Kit for Intraflagellar Transport Protein 172 (IFT172) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Intraflagellar Transport Protein 172 (IFT172) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Intraflagellar Transport Protein 172 (IFT172) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Intraflagellar Transport Protein 172 (IFT172) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Intraflagellar Transport Protein 172 (IFT172) CLIA Kit Customized Service Offer
n/a ELISA Kit for Intraflagellar Transport Protein 172 (IFT172) ELISA Kit Customized Service Offer
  1. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  4. "Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain."DNA Res. 6:329-336(1999) [PubMed] [Europe PMC] [Abstract]
  5. "In vivo identification of sumoylation sites by a signature tag and cysteine-targeted affinity purification."J. Biol. Chem. 285:19324-19329(2010) [PubMed] [Europe PMC] [Abstract]
  6. "Defects in the IFT-B component IFT172 cause Jeune and Mainzer-Saldino syndromes in humans." Am. J. Hum. Genet. 93:915-925(2013) [PubMed] [Europe PMC] [Abstract]