Synaptotagmin XIV Like Protein (SYT14L)

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SYTDEP; CHR415SYT; Synaptotagmin XIV-derived protein

Synaptotagmin XIV Like Protein (SYT14L)
SYTDEP contains 3 N-glycosylation sites, an O-glycosylation site, a number of potential serine, threonine, and tyrosine phosphorylation sites, 3 N-terminal cysteine residues that might be fatty-acylated, and a single C2B domain. The N-terminal 24 amino acids of SYTDEP showed no significant homology with any known protein domain.
Sequence analysis suggested that, like SYT14, SYTDEP is a calcium-independent C2 protein. RT-PCR analysis showed that SYTDEP was highly expressed in mature peripheral blood neutrophils and became upregulated during neutrophil differentiation of HL-60 cells that did not express SYT14. GOS-3 cells expressed both SYTDEP and SYT14. Western blot analysis of neutrophils detected a 27-kD protein, suggesting posttranslational modification.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Synaptotagmin XIV Like Protein (SYT14L) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Synaptotagmin XIV Like Protein (SYT14L) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Synaptotagmin XIV Like Protein (SYT14L) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Synaptotagmin XIV Like Protein (SYT14L) CLIA Kit Customized Service Offer
n/a ELISA Kit for Synaptotagmin XIV Like Protein (SYT14L) ELISA Kit Customized Service Offer
  1. "Cloning and genomic characterization of sytdep, a new synaptotagmin XIV-related gene."Biochem. Biophys. Res. Commun. 340:386-394(2006) [PubMed] [Europe PMC] [Abstract]
  2. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Genomic analysis of synaptotagmin genes."Genomics 77:43-49(2001) [PubMed] [Europe PMC] [Abstract].