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Pleckstrin Homology Domain Containing Family A, Member 5 (PLEKHA5)

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PEPP2; Phosphoinositol 3-phosphate-binding protein 2

Pleckstrin Homology Domain Containing Family A, Member 5 (PLEKHA5)
CCC M561
HGNC 30036
MGI 1923802
PubMed 11214970
UniProt Q9HAU0
Wiki PLEKHA5
The deduced 1,060-amino acid PEPP2 protein contains 2 WW domains followed by a pleckstrin homology (PH) domain at its N terminus. It shares significant homology with PEPP1 and PEPP3 only within the PH domain. Northern blot analysis detected expression of a 4.6-kb transcript at high levels in heart and kidney and at lower levels in all other normal tissues examined. Expression was also detected in some cancer tissues.
The 3-prime untranslated region contains several SINEs, including Alu and MIR sequences. RT-PCR ELISA detected expression of PEPP2 at highest levels in ovary and at intermediate levels in all other adult tissues, fetal tissues, and specific adult brain regions examined.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Pleckstrin Homology Domain Containing Family A, Member 5 (PLEKHA5) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Pleckstrin Homology Domain Containing Family A, Member 5 (PLEKHA5) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Pleckstrin Homology Domain Containing Family A, Member 5 (PLEKHA5) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Pleckstrin Homology Domain Containing Family A, Member 5 (PLEKHA5) CLIA Kit Customized Service Offer
n/a ELISA Kit for Pleckstrin Homology Domain Containing Family A, Member 5 (PLEKHA5) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Pleckstrin Homology Domain Containing Family A, Member 5 (PLEKHA5) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Pleckstrin Homology Domain Containing Family A, Member 5 (PLEKHA5) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Pleckstrin Homology Domain Containing Family A, Member 5 (PLEKHA5) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Pleckstrin Homology Domain Containing Family A, Member 5 (PLEKHA5) CLIA Kit Customized Service Offer
n/a ELISA Kit for Pleckstrin Homology Domain Containing Family A, Member 5 (PLEKHA5) ELISA Kit Customized Service Offer
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  11. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  12. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  13. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  14. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  15. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  16. "Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features."Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012) [PubMed] [Europe PMC] [Abstract]
  17. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  18. "Solution structure of the PH domain of pleckstrin homology domain-containing protein family A member 5 from human."Submitted (OCT-2006) to the PDB data bank