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DDB1 And CUL4 Associated Factor 7 (DCAF7)

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WDR68; HAN11; AN11; SWAN-1; WD Repeat Domain 68; Seven WD Repeat Protein Of The AN11 Family-1

DDB1 And CUL4 Associated Factor 7 (DCAF7)
CCC M552
HGNC 30915
MGI 1919083
PubMed 20940704
RGD 1305140
UniProt P61962
The An1, An2, and An11 loci control the pigmentation of petunias by stimulating transcription of anthocyanin genes. By Southern blot analysis with a petunia An11 probe, followed by EST database searching and PCR, de Vetten et al. (1997) obtained a cDNA encoding human AN11.
The deduced 342-amino acid, WD repeat-containing protein is 53% identical to the petunia An11 protein and is conserved in worms and yeast, which do not produce anthocyanins. Functional analysis showed that human AN11 could partially complement a petunia An11 mutant. De Vetten et al. (1997) concluded that An11 is involved in signal transduction in petunias.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant DDB1 And CUL4 Associated Factor 7 (DCAF7) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to DDB1 And CUL4 Associated Factor 7 (DCAF7) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to DDB1 And CUL4 Associated Factor 7 (DCAF7) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for DDB1 And CUL4 Associated Factor 7 (DCAF7) CLIA Kit Customized Service Offer
n/a ELISA Kit for DDB1 And CUL4 Associated Factor 7 (DCAF7) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant DDB1 And CUL4 Associated Factor 7 (DCAF7) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to DDB1 And CUL4 Associated Factor 7 (DCAF7) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to DDB1 And CUL4 Associated Factor 7 (DCAF7) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for DDB1 And CUL4 Associated Factor 7 (DCAF7) CLIA Kit Customized Service Offer
n/a ELISA Kit for DDB1 And CUL4 Associated Factor 7 (DCAF7) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant DDB1 And CUL4 Associated Factor 7 (DCAF7) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to DDB1 And CUL4 Associated Factor 7 (DCAF7) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to DDB1 And CUL4 Associated Factor 7 (DCAF7) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for DDB1 And CUL4 Associated Factor 7 (DCAF7) CLIA Kit Customized Service Offer
n/a ELISA Kit for DDB1 And CUL4 Associated Factor 7 (DCAF7) ELISA Kit Customized Service Offer
  1. "The an11 locus controlling flower pigmentation in petunia encodes a novel WD-repeat protein conserved in yeast, plants, and animals."Genes Dev. 11:1422-1434(1997) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage." Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Phosphorylation of Ser640 in muscle glycogen synthase by DYRK family protein kinases."J. Biol. Chem. 279:2490-2498(2004) [PubMed] [Europe PMC] [Abstract]
  6. "HAN11 binds mDia1 and controls GLI1 transcriptional activity."J. Dermatol. Sci. 44:11-20(2006) [PubMed] [Europe PMC] [Abstract]
  7. "A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1."Mol. Cell 23:709-721(2006) [PubMed] [Europe PMC] [Abstract]
  8. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  9. "ZNF703 gene amplification at 8p12 specifies luminal B breast cancer." EMBO Mol. Med. 3:153-166(2011) [PubMed] [Europe PMC] [Abstract]