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Rearranged L-Myc Fusion (RLF)

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ZNF292L; Zn-15L; Zn-15-related protein; Zinc finger protein Rlf; LMyc Fusion

Rearranged L-Myc Fusion (RLF)
CCC M538
HGNC 10025
MGI 1924705
PubMed 8545128
RGD 1305297
UniProt Q13129
Wiki RLF

In 2 independent small cell lung carcinoma (SCLC) cell lines, Makela et al. (1991) found similar novel proteins antigenically related to LMYC. cDNAs corresponding to these proteins were cloned and shown to encode chimeric polypeptides with amino-terminal sequences from a novel gene named RLF (rearranged LMYC fusion) joined to the LMYC protein.

Makela et al. (1991) presented the preliminary characterization of the RLF/LMYC fusion gene which has been found only in cells with an amplified LMYC gene. The presence of independent genetic lesions caused the formation of identical chimeric RLF/LMYC proteins and suggested a role for the fusion protein in the development of tumors.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Rearranged L-Myc Fusion (RLF) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Rearranged L-Myc Fusion (RLF) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Rearranged L-Myc Fusion (RLF) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Rearranged L-Myc Fusion (RLF) CLIA Kit Customized Service Offer
n/a ELISA Kit for Rearranged L-Myc Fusion (RLF) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Rearranged L-Myc Fusion (RLF) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Rearranged L-Myc Fusion (RLF) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Rearranged L-Myc Fusion (RLF) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Rearranged L-Myc Fusion (RLF) CLIA Kit Customized Service Offer
n/a ELISA Kit for Rearranged L-Myc Fusion (RLF) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Rearranged L-Myc Fusion (RLF) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Rearranged L-Myc Fusion (RLF) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Rearranged L-Myc Fusion (RLF) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Rearranged L-Myc Fusion (RLF) CLIA Kit Customized Service Offer
n/a ELISA Kit for Rearranged L-Myc Fusion (RLF) ELISA Kit Customized Service Offer
  1. "The rearranged L-myc fusion gene (RLF) encodes a Zn-15 related zinc finger protein."Oncogene 11:2699-2704(1995) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence and biological annotation of human chromosome 1." Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
  5. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  6. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]