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Potassium Channel Modulatory Factor 1 (KCMF1)

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PCMF; ZZZ1; DEBT91; E3 ubiquitin-protein ligase KCMF1; FGF-induced in gastric cancer; ZZ-type zinc finger-containing protein 1

Potassium Channel Modulatory Factor 1 (KCMF1)
CCC M523
HGNC 20589
MGI 1921537
PubMed 23600395
UniProt Q9P0J7
CD99 suppression resulted in growth inhibition and reduced migration of ESFT cells. Among genes whose expression changes in response to CD99 modulation, the potassium-channel modulatory factor KCMF1 was consistently upregulated. In a series of 22 primary ESFT, KCMF1 expression levels inversely correlated with CD99 abundancy.
Cells forced to express ectopic KCMF1 showed a similar reduction in migratory ability as CD99 silenced ESFT cells. In ESFT, high CD99 expression levels contribute to the malignant properties of ESFT by promoting growth and migration of tumor cells and identify KCMF1 as a potential metastasis suppressor gene downregulated by high constitutive CD99 expression in ESFT.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Potassium Channel Modulatory Factor 1 (KCMF1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Potassium Channel Modulatory Factor 1 (KCMF1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Potassium Channel Modulatory Factor 1 (KCMF1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Potassium Channel Modulatory Factor 1 (KCMF1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Potassium Channel Modulatory Factor 1 (KCMF1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Potassium Channel Modulatory Factor 1 (KCMF1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Potassium Channel Modulatory Factor 1 (KCMF1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Potassium Channel Modulatory Factor 1 (KCMF1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Potassium Channel Modulatory Factor 1 (KCMF1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Potassium Channel Modulatory Factor 1 (KCMF1) ELISA Kit Customized Service Offer
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