Canopy 2 Homolog (CNPY2)

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ZSIG9; Cnpy2; MSAP; TMEM4; Transmembrane Protein 4; MIR-interacting saposin-like protein; Putative secreted protein Zsig9

Canopy 2 Homolog (CNPY2)
TMEM4 encodes a predicted 182-amino acid type II transmembrane protein.The first 3 to 20 amino acids of MSAP constitute the SA region, which is followed by a saposin -like domain interrupted by 2 stretches of 30 and 40 amino acids.
Northern blot analysis detected MSAP expression in all adult and fetal tissues examined, with highest levels in adult placenta, liver, and pancreas. Western blot analysis of placenta and brain detected MSAP at an apparent molecular mass of 21 kD. Immunofluorescence microscopy showed colocalization of Msap with Mir in COS-7 cells. In cultured rodent primary hippocampal neurons, the 2 proteins localized around the nucleus and extended into the neurites.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPM449Hu01 Recombinant Canopy 2 Homolog (CNPY2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAM449Hu21 Monoclonal Antibody to Canopy 2 Homolog (CNPY2) WB; IHC; ICC; IP.
PAM449Hu01 Polyclonal Antibody to Canopy 2 Homolog (CNPY2) WB,IHC,ICC/IF
Assay Kits SEM449Hu ELISA Kit for Canopy 2 Homolog (CNPY2) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPM449Mu01 Recombinant Canopy 2 Homolog (CNPY2) Positive Control; Immunogen; SDS-PAGE; WB.
RPM449Mu02 Recombinant Canopy 2 Homolog (CNPY2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAM449Mu01 Polyclonal Antibody to Canopy 2 Homolog (CNPY2) WB; IHC; ICC; IP.
PAM449Mu02 Polyclonal Antibody to Canopy 2 Homolog (CNPY2) WB; IHC; ICC; IP.
Assay Kits SEM449Mu ELISA Kit for Canopy 2 Homolog (CNPY2) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Canopy 2 Homolog (CNPY2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Canopy 2 Homolog (CNPY2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Canopy 2 Homolog (CNPY2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Canopy 2 Homolog (CNPY2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Canopy 2 Homolog (CNPY2) ELISA Kit Customized Service Offer
  1. "Selection of cDNAs encoding putative type II membrane proteins on the cell surface from a human full-length cDNA bank."Gene 228:161-167(1999) [PubMed] [Europe PMC] [Abstract]
  2. "MSAP is a novel MIR-interacting protein that enhances neurite outgrowth and increases myosin regulatory light chain."J. Biol. Chem. 278:35412-35420(2003) [PubMed] [Europe PMC] [Abstract]
  3. "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]