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E74 Like Factor 1 (ELF1)

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ETS-related transcription factor Elf-1

E74 Like Factor 1 (ELF1)
CCC M437
HGNC 3316
MGI 107180
PubMed 21044949
RGD 620697
UniProt P32519
ELF1 contains a sequence motif that is highly related to the RB (retinoblastoma) binding sites of several viral oncoproteins and binds to the pocket region of RB1 both in vitro and in vivo. Other results demonstrated that RB interacts specifically with this lineage-restricted ETS transcription factor. The interaction may be important for the coordination of lineage-specific effector functions.
RAGS and ELF1, both ligands for EPH-related receptor tyrosine kinases, have been implicated in the control of development of the retinotectal projection. ELF1 has a repellent axon guidance function for temporal, but apparently not for nasal, axons. RAGS, on the other hand, is repellent for both types of axons, though to different degrees.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant E74 Like Factor 1 (ELF1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to E74 Like Factor 1 (ELF1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to E74 Like Factor 1 (ELF1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for E74 Like Factor 1 (ELF1) CLIA Kit Customized Service Offer
n/a ELISA Kit for E74 Like Factor 1 (ELF1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant E74 Like Factor 1 (ELF1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to E74 Like Factor 1 (ELF1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to E74 Like Factor 1 (ELF1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for E74 Like Factor 1 (ELF1) CLIA Kit Customized Service Offer
n/a ELISA Kit for E74 Like Factor 1 (ELF1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant E74 Like Factor 1 (ELF1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to E74 Like Factor 1 (ELF1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to E74 Like Factor 1 (ELF1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for E74 Like Factor 1 (ELF1) CLIA Kit Customized Service Offer
n/a ELISA Kit for E74 Like Factor 1 (ELF1) ELISA Kit Customized Service Offer
  1. "A novel Ets-related transcription factor, Elf-1, binds to human immunodeficiency virus type 2 regulatory elements that are required for inducible trans activation in T cells."J. Virol. 66:5890-5897(1992) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence and analysis of human chromosome 13." Nature 428:522-528(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Cis-acting sequences required for inducible interleukin-2 enhancer function bind a novel Ets-related protein, Elf-1."Mol. Cell. Biol. 12:1043-1053(1992) [PubMed] [Europe PMC] [Abstract]
  6. "Regulation of the Ets-related transcription factor Elf-1 by binding to the retinoblastoma protein."Science 260:1330-1335(1993) [PubMed] [Europe PMC] [Abstract]
  7. "Characterization of NERF, a novel transcription factor related to the Ets factor ELF-1."Mol. Cell. Biol. 16:5091-5106(1996) [PubMed] [Europe PMC] [Abstract]
  8. "Cloning of a novel human ELF-1-related ETS transcription factor, ELFR, its characterization and chromosomal assignment relative to ELF-1."Gene 210:71-78(1998) [PubMed] [Europe PMC] [Abstract]
  9. "Functional and physical interactions between AML1 proteins and an ETS protein, MEF: implications for the pathogenesis of t(8;21)-positive leukemias."Mol. Cell. Biol. 19:3635-3644(1999) [PubMed] [Europe PMC] [Abstract]
  10. "A probability-based approach for high-throughput protein phosphorylation analysis and site localization."Nat. Biotechnol. 24:1285-1292(2006) [PubMed] [Europe PMC] [Abstract]
  11. "ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage."Science 316:1160-1166(2007) [PubMed] [Europe PMC] [Abstract]
  12. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  13. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  14. "Large-scale proteomics analysis of the human kinome."Mol. Cell. Proteomics 8:1751-1764(2009) [PubMed] [Europe PMC] [Abstract]
  15. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  16. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  17. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]