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Ts Translation Elongation Factor, Mitochondrial (TSFM)

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COXPD3; EF-TS; EF-Tsmt

Ts Translation Elongation Factor, Mitochondrial (TSFM)
CCC M404
HGNC 12367
MGI 1913649
PubMed 7615523
UniProt P43897
Wiki TSFM
The TSFM cDNA, which lacks 5-prime coding sequence, encodes a portion of the putative N-terminal mitochondrial signal peptide and a predicted 283-amino acid mature protein. The mature human TSFM protein shares 91% amino acid sequence identity with mature bovine EFTsMT and 29% identity with E. coli EFTs.
Northern blot analysis of human tissues detected an approximately 1.2-kb TSFM transcript in all tissues tested. Skeletal muscle had the most abundant level, followed by liver, kidney, and heart. Placenta, brain, pancreas, and lung had substantially lower levels. Skeletal muscle contained an additional, larger transcript that was also observed at lower levels in several other tissues.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Ts Translation Elongation Factor, Mitochondrial (TSFM) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Ts Translation Elongation Factor, Mitochondrial (TSFM) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Ts Translation Elongation Factor, Mitochondrial (TSFM) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Ts Translation Elongation Factor, Mitochondrial (TSFM) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ts Translation Elongation Factor, Mitochondrial (TSFM) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Ts Translation Elongation Factor, Mitochondrial (TSFM) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Ts Translation Elongation Factor, Mitochondrial (TSFM) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Ts Translation Elongation Factor, Mitochondrial (TSFM) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Ts Translation Elongation Factor, Mitochondrial (TSFM) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ts Translation Elongation Factor, Mitochondrial (TSFM) ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The finished DNA sequence of human chromosome 12." Nature 440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Cloning and expression of mitochondrial translational elongation factor Ts from bovine and human liver."J. Biol. Chem. 270:17243-17249(1995) [PubMed] [Europe PMC] [Abstract]
  5. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  6. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  7. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  8. "Solution structure of RSGI RUH-042, a UBA domain from human mitochondrial elongation factor TS."Submitted (NOV-2005) to the PDB data bank
  9. "Distinct clinical phenotypes associated with a mutation in the mitochondrial translation elongation factor EFTs."Am. J. Hum. Genet. 79:869-877(2006) [PubMed] [Europe PMC] [Abstract]
  10. "Genomic analysis of mitochondrial diseases in a consanguineous population reveals novel candidate disease genes."J. Med. Genet. 49:234-241(2012) [PubMed] [Europe PMC] [Abstract]