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Thymus High Mobility Group Box Protein 3 (TOX3)

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TNRC9; CAGF9; CAG trinucleotide repeat-containing gene F9 protein; Trinucleotide repeat-containing gene 9 protein

Thymus High Mobility Group Box Protein 3 (TOX3)
CCC M383
HGNC 11972
MGI 3039593
PubMed 21172805
RGD 1311529
UniProt O15405
Wiki TOX3
TOX3 belongs to the large and diverse family of HMG-box proteins that function as architectural factors in the modification of chromatin structure by bending and unwinding DNA.
The deduced 576-amino acid protein has a calculated molecular mass of 63.3 kD. It has a central lysine-rich nuclear localization signal followed by an HMG box. TOX3 shares a high degree of similarity with the mouse Tox3 protein, with the exception of a trinucleotide repeat coding for glutamine in the C terminus that is not found in the mouse.TNRC9 was one of 69 genes that was differentially expressed in patients who experienced breast cancer relapse to bone versus those who experienced relapse elsewhere in the body.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Thymus High Mobility Group Box Protein 3 (TOX3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Thymus High Mobility Group Box Protein 3 (TOX3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Thymus High Mobility Group Box Protein 3 (TOX3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Thymus High Mobility Group Box Protein 3 (TOX3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Thymus High Mobility Group Box Protein 3 (TOX3) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Thymus High Mobility Group Box Protein 3 (TOX3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Thymus High Mobility Group Box Protein 3 (TOX3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Thymus High Mobility Group Box Protein 3 (TOX3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Thymus High Mobility Group Box Protein 3 (TOX3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Thymus High Mobility Group Box Protein 3 (TOX3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Thymus High Mobility Group Box Protein 3 (TOX3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Thymus High Mobility Group Box Protein 3 (TOX3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Thymus High Mobility Group Box Protein 3 (TOX3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Thymus High Mobility Group Box Protein 3 (TOX3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Thymus High Mobility Group Box Protein 3 (TOX3) ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The sequence and analysis of duplication-rich human chromosome 16." Nature 432:988-994(2004) [PubMed] [Europe PMC] [Abstract]
  3. "cDNAs with long CAG trinucleotide repeats from human brain."Hum. Genet. 100:114-122(1997) [PubMed] [Europe PMC] [Abstract]
  4. "TOX3 is a neuronal survival factor that induces transcription depending on the presence of CITED1 or phosphorylated CREB in the transcriptionally active complex."J. Cell Sci. 124:252-260(2011) [PubMed] [Europe PMC] [Abstract]