The deduced 1,203-amino acid protein contains an RNA recognition motif. RT-PCR ELISA detected moderate expression in all tissues and specific brain regions examined, with highest expression in cerebellum.
Schneider et al. (2006) stated that the 1,727-amino acid TNRC6B protein contains a glycine/tryptophan (GW)-rich N-terminal domain, a central glutamine-rich region, and a C-terminal RNA recognition motif.
TNRC6B copurified with a cytoplasmic HeLa cell protein complex containing AGO2 (EIF2C2), DICER, and MOV10. Epitope-tagged TNRC6B coimmunoprecipitated with tagged AGO1 (EIF2C1) and tagged AGO2. TNRC6B was required to mediate microRNA-guided mRNA cleavage in HeLa cell culture.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Trinucleotide Repeat Containing Protein 6B (TNRC6B) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Trinucleotide Repeat Containing Protein 6B (TNRC6B) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Trinucleotide Repeat Containing Protein 6B (TNRC6B) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Trinucleotide Repeat Containing Protein 6B (TNRC6B) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Trinucleotide Repeat Containing Protein 6B (TNRC6B) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Trinucleotide Repeat Containing Protein 6B (TNRC6B) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Trinucleotide Repeat Containing Protein 6B (TNRC6B) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Trinucleotide Repeat Containing Protein 6B (TNRC6B) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Trinucleotide Repeat Containing Protein 6B (TNRC6B) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Trinucleotide Repeat Containing Protein 6B (TNRC6B) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Trinucleotide Repeat Containing Protein 6B (TNRC6B) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Trinucleotide Repeat Containing Protein 6B (TNRC6B) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Trinucleotide Repeat Containing Protein 6B (TNRC6B) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Trinucleotide Repeat Containing Protein 6B (TNRC6B) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Trinucleotide Repeat Containing Protein 6B (TNRC6B) | ELISA Kit Customized Service Offer |
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