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Transducin Like Enhancer Of Split 4 (TLE4)

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ESG; BCE-1; E(spI); ESG4; GRG4; Groucho-related protein 4

Transducin Like Enhancer Of Split 4 (TLE4)
CCC M370
HGNC 11840
MGI 104633
PubMed 18258796
RGD 3868
UniProt Q04727
Wiki TLE4
Enhancer of split is a complex locus composed of several genetically related transcription factors implicated in cell fate decision and boundary formation. Sequence analysis predicted that the TLE4 protein contains SP and WD40 domains. Northern blot analysis detected a major 5.1- and a minor 2.8-kb TLE4 transcript predominantly in brain and muscle.The predicted TLE4 protein contains 787 amino acids. RT-PCR analysis detected TLE4 expression in all tissues tested, with highest expression in brain, particularly in the caudate nucleus.The TLE4 transcripts were approximately 4.4 and 3.4 kb. The QD transcripts were restricted to pro- and pre-B-cell lines. Immunocytochemical analysis demonstrated punctate nuclear TLE4 expression in pro-, pre-, and mature B-cell lines.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
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Antibodies n/a Monoclonal Antibody to Transducin Like Enhancer Of Split 4 (TLE4) Monoclonal Antibody Customized Service Offer
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Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Transducin Like Enhancer Of Split 4 (TLE4) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Transducin Like Enhancer Of Split 4 (TLE4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Transducin Like Enhancer Of Split 4 (TLE4) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Transducin Like Enhancer Of Split 4 (TLE4) CLIA Kit Customized Service Offer
n/a ELISA Kit for Transducin Like Enhancer Of Split 4 (TLE4) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Transducin Like Enhancer Of Split 4 (TLE4) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Transducin Like Enhancer Of Split 4 (TLE4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Transducin Like Enhancer Of Split 4 (TLE4) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Transducin Like Enhancer Of Split 4 (TLE4) CLIA Kit Customized Service Offer
n/a ELISA Kit for Transducin Like Enhancer Of Split 4 (TLE4) ELISA Kit Customized Service Offer
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  16. "Mutations in PAX2 associate with adult-onset FSGS."J. Am. Soc. Nephrol. 25:1942-1953(2014) [PubMed] [Europe PMC] [Abstract]
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